Evidence map›Paper›PMID 31310125›Full record

ArticleJournal of medicinal chemistry2019

2-Amino-2,3-dihydro-1

Dongsheng Zhu, Huocong Huang, Daniel M Pinkas, Jinfeng Luo, Debolina Ganguly, Alice E Fox, Emily Arner, Qiuping Xiang, Zheng-Chao Tu, Alex N Bullock and 3 more

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of medicinal chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
4.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 60 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 3 countries.

Dongsheng ZhuInternational Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug Development of Chinese Ministry of Education (MOE), School of Pharmacy , Jinan University , 601 Huangpu Avenue West , Guangzhou 510632 , China.
Huocong HuangDivision of Surgical Oncology, Department of Surgery and Hamon Center for Therapeutic Oncology Research , UT Southwestern , Dallas , Texas 75390-8593 , United States.
Daniel M PinkasStructural Genomics Consortium , University of Oxford , Old Road Campus Research Building, Roosevelt Drive , Oxford OX3 7DQ , U.K.
Jinfeng LuoGuangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences , 190 Kaiyuan Avenue , Guangzhou 510530 , China.
Debolina GangulyDivision of Surgical Oncology, Department of Surgery and Hamon Center for Therapeutic Oncology Research , UT Southwestern , Dallas , Texas 75390-8593 , United States.
Alice E FoxStructural Genomics Consortium , University of Oxford , Old Road Campus Research Building, Roosevelt Drive , Oxford OX3 7DQ , U.K.
Emily ArnerDivision of Surgical Oncology, Department of Surgery and Hamon Center for Therapeutic Oncology Research , UT Southwestern , Dallas , Texas 75390-8593 , United States.
Qiuping XiangGuangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences , 190 Kaiyuan Avenue , Guangzhou 510530 , China.
Zheng-Chao TuGuangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences , 190 Kaiyuan Avenue , Guangzhou 510530 , China.
Alex N BullockStructural Genomics Consortium , University of Oxford , Old Road Campus Research Building, Roosevelt Drive , Oxford OX3 7DQ , U.K.
Rolf A BrekkenDivision of Surgical Oncology, Department of Surgery and Hamon Center for Therapeutic Oncology Research , UT Southwestern , Dallas , Texas 75390-8593 , United States.
Ke DingInternational Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug Development of Chinese Ministry of Education (MOE), School of Pharmacy , Jinan University , 601 Huangpu Avenue West , Guangzhou 510632 , China.ORCID 0000-0001-9016-812X
Xiaoyun LuInternational Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug Development of Chinese Ministry of Education (MOE), School of Pharmacy , Jinan University , 601 Huangpu Avenue West , Guangzhou 510632 , China.ORCID 0000-0001-7931-6873
The University of Texas Southwestern Medical Center · USChinese Academy of Sciences · CNJinan University · CNUniversity of Oxford · GB

Funding

Wellcome TrustWellcome Trust 106169/ZZ14/Z
6 · The paper itself

Abstract

A series of 2-amino-2,3-dihydro-1

Indexed as

AnimalsAntineoplastic AgentsCell Line, TumorDiscoidin Domain Receptor 1Drug DesignEpithelial-Mesenchymal TransitionHumansMaleMice, Inbred C57BLNeoplasms, ExperimentalPancreatic NeoplasmsRats, Sprague-DawleyTumor Stem Cell AssayXenograft Model Antitumor AssaysAntineoplastic AgentsDiscoidin Domain Receptor 1

Identifiers

PMID31310125
PMCPMC6985936
OpenAlexW2956266977

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.