Evidence map›Paper›PMID 31309977›Full record

Trial reportPhysical therapy2019

Aerobic and Resistance Exercise Improves Shoulder Function in Women Who Are Overweight or Obese and Have Breast Cancer: A Randomized Controlled Trial.

Frank C Sweeney, Wendy Demark-Wahnefried, Kerry S Courneya, Nathalie Sami, Kyuwan Lee, Debu Tripathy, Kimiko Yamada, Thomas A Buchanan, Darcy V Spicer, Leslie Bernstein and 2 more

Open access · bronzeAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Physical therapy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 6 pooled it
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 6 syntheses or guidelines pooled it, 56 citations in OpenAlex.

  1. Pooled it
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  7. Effects of combined exercises on shoulder mobility and strength of the upper extremities in breast cancer rehabilitation: a 3-week randomized controlled trial.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023
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  11. The role of digital rehabilitation therapy in enhancing upper limb function recovery following surgery in breast cancer patients.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 2 countries.

Frank C SweeneyDivision of Biokinesiology and Physical Therapy, University of Southern California, Los Angeles, California.
Wendy Demark-WahnefriedDepartment of Nutrition Sciences, University of Alabama at Birmingham, Birmingham, Alabama.
Kerry S CourneyaFaculty of Kinesiology, Sport, and Recreation, University of Alberta, Edmonton, Alberta, Canada.
Nathalie SamiDivision of Biokinesiology and Physical Therapy, University of Southern California, Los Angeles, California.
Kyuwan LeeDivision of Biokinesiology and Physical Therapy, University of Southern California, Los Angeles, California.
Debu TripathyDepartment of Breast Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Kimiko YamadaDivision of Biokinesiology and Physical Therapy, University of Southern California, Los Angeles, California.
Thomas A BuchananDivision of Endocrinology and Diabetes, Keck School of Medicine, University of Southern California.
Darcy V SpicerDepartment of Medicine, Keck School of Medicine, University of Southern California.
Leslie BernsteinDivision of Biomarkers of Early Detection and Prevention, Beckman Research Institute, City of Hope, Duarte, California.
Joanne E MortimerDivision of Medical Oncology and Experimental Therapeutics, City of Hope.
Christina M Dieli-ConwrightDepartment of Supportive Care Medicine, City of Hope, 1500 East Duarte Road, Duarte, CA 91010 (USA).
University of Southern California · USCity of Hope · USBeckman Research InstituteThe University of Texas MD Anderson Cancer Center · USUniversity of Alabama at Birmingham · USUniversity of Alberta · CA

Funding

Southern California Clinical and Translational Science InstituteUL1TR001855 · NCATS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Thomas A Buchanan, Michele D. Kipke · 2016 to 2026
$81.3M
Southern California Clinical and Translational Science InstituteUL1TR000130 · NCATS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI BUCHANAN, THOMAS A · 2012 to 2015
$36.0M
Why is the prevalence of obesity so high in U.S. Southern States? Regional predictors of BMI and obesity treatment response.P30DK056336 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI BARBARA A GOWER · 2000 to 2026
$31.9M
Metabolic Syndrome and Breast Cancer: Effects of a Combined Exercise InterventionK07CA160718 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI DIELI-CONWRIGHT, CHRISTINA · 2011 to 2015
$629k
NCATS NIH HHS UL1 TR000130NCATS NIH HHS UL1 TR001855NCI NIH HHS K07 CA160718NIDDK NIH HHS P30 DK056336
6 · The paper itself

Abstract

backgroundAdverse upper limb musculoskeletal effects occur after surgical procedures and radiotherapy for breast cancer and can interfere with activities of daily living.

objectiveThe objective of this study was to examine the effects of a 16-week exercise intervention on shoulder function in women who are overweight or obese and have breast cancer.

designThis study was a randomized controlled trial.

settingThe study was performed at the Division of Biokinesiology and Physical Therapy at the University of Southern California.

participantsOne hundred women with breast cancer were randomly allocated to exercise or usual-care groups. The mean (SD) age of the women was 53.5 (10.4) years, 55% were Hispanic white, and their mean (SD) body mass index was 33.5 (5.5) kg/m2.

interventionThe 16-week exercise intervention consisted of supervised, progressive, moderate to vigorous aerobic and resistance exercise 3 times per week. MEASUREMENTS: Shoulder active range of motion, isometric muscular strength, and patient-reported outcome measures (including Disabilities of the Arm, Shoulder, and Hand and the Penn Shoulder Scale) were assessed at baseline, after the intervention, and at the 3-month follow-up (exercise group only). Differences in mean changes for outcomes were evaluated using mixed-model repeated-measures analysis.

resultsCompared with the usual-care group, the exercise group experienced significant increases in shoulder active range of motion (the mean between-group differences and 95% confidence intervals (CIs) were as follows: shoulder flexion = 36.6° [95% CI = 55.2-20.7°], external rotation at 0° = 23.4° [95% CI = 31.1-12.5°], and external rotation at 90° = 34.3° [95% CI = 45.9-26.2°]), improved upper extremity isometric strength, and improved Disabilities of the Arm, Shoulder, and Hand and Penn Shoulder Scale scores. LIMITATIONS: Limitations include a lack of masking of assessors after the intervention, an attention control group, and statistical robustness (shoulder function was a secondary end point).

conclusionsA 16-week exercise intervention effectively improved shoulder function following breast cancer treatment in women who were overweight or obese, who were ethnically diverse, and who had breast cancer.

Indexed as

Activities of Daily LivingBreast NeoplasmsCancer SurvivorsExercise TherapyFemaleHumansMiddle AgedObesityRange of Motion, ArticularResistance TrainingShoulder Joint

Identifiers

PMID31309977
PMCPMC6821226
OpenAlexW2961003428

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.