Evidence map›Paper›PMID 31309920›Full record

ArticleThe American journal of tropical medicine and hygiene2019

Investigating Possible Infectious Causes of Chronic Kidney Disease of Unknown Etiology in a Nicaraguan Mining Community.

W Katherine Yih, Martin Kulldorff, David J Friedman, Jessica H Leibler, Juan José Amador, Damaris López-Pilarte, Renee L Galloway, Oriana Ramírez-Rubio, Alejandro Riefkohl, Daniel R Brooks

Abstract read
In one paragraph

Article in The American journal of tropical medicine and hygiene, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Genetic risk factors for Mesoamerican nephropathy.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  6. American journal of physiology. Renal physiology · 2024
    Article
  7. Article
  8. Article
  9. Article
  10. Workplace Intervention for Heat Stress: Essential Elements of Design, Implementation, and Assessment.International journal of environmental research and public health · 2022
    Article
  11. Review
  12. Review
  13. Article
  14. Article
  15. Article
  16. Chronic kidney disease of non-traditional origin in Mesoamerica: a disease primarily driven by occupational heat stress.Revista panamericana de salud publica = Pan American journal of public health · 2020
    Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

W Katherine YihDepartment of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, Massachusetts.
Martin KulldorffDivision of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Harvard Medical School and Brigham and Women's Hospital, Boston, Massachusetts.
David J FriedmanDivision of Nephrology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts.
Jessica H LeiblerDepartment of Environmental Health, Boston University School of Public Health, Boston, Massachusetts.
Juan José AmadorDepartment of Epidemiology, Boston University School of Public Health, Boston, Massachusetts.
Damaris López-PilarteDepartment of Epidemiology, Boston University School of Public Health, Boston, Massachusetts.
Renee L GallowayCenters for Disease Control and Prevention, Atlanta, Georgia.
Oriana Ramírez-RubioDepartment of Epidemiology, Boston University School of Public Health, Boston, Massachusetts.
Alejandro RiefkohlDepartment of Epidemiology, Boston University School of Public Health, Boston, Massachusetts.
Daniel R BrooksDepartment of Epidemiology, Boston University School of Public Health, Boston, Massachusetts.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A chronic kidney disease of unknown etiology (CKDu) has been killing workers in Central America. Occupational heat stress is thought to play an important role. Leptospirosis and hantavirus have been suggested as additional possible risk factors. In a case-control study in a Nicaraguan mining community, a structured survey was administered to adults, and biological measurements and specimens were taken. Serum was analyzed for antibodies to

Indexed as

MiningPublic HealthAdultAgedCase-Control StudiesCreatinineFemaleHantavirus InfectionsHumansLeptospiraLeptospirosisMaleMiddle AgedNicaraguaOrthohantavirusProspective StudiesCreatinine

Identifiers

PMID31309920
PMCPMC6726956

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.