ArticleInternational psychogeriatrics2019
Validation of neuropsychological tests for the China Health and Retirement Longitudinal Study Harmonized Cognitive Assessment Protocol.
Article in International psychogeriatrics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 68 papers.
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68 citing papers in PubMed, 118 citations in OpenAlex.
- Sleep quality modifies the association between nocturnal sleep, daytime napping, and mild cognitive impairment: A population-based dose-response study.Sleep medicine: X · 2026Article
- Does Socioeconomic Status Moderate the Association Between Metabolic Syndrome and Cognitive Decline? A Moderated Mediation Analysis Using the China Health and Retirement Longitudinal Study (CHARLS).Research square · 2026Article
- Low-burden AI approach for cross-national early identification of cognitive impairment using real-world questionnaire response behaviours.Nature communications · 2026Article
- Impact of body roundness index on cognitive decline and cognitive impairment in middle-aged and older adults ≥ 45 years: mediating role of biological aging.Scientific reports · 2026Article
- Intrinsic capacity and the risk of adverse health outcomes in older adults: a population-based study.BMC geriatrics · 2026Article
- Is all movement equal at every age? Differentiating the impact of physical activity types on depressive symptoms and mental acuity in an aging India.Archives of public health = Archives belges de sante publique · 2026Article
- Longitudinal association between the weekend warrior physical activity pattern and cognitive function trajectories among middle-aged and older Chinese adults.Archives of public health = Archives belges de sante publique · 2026Article
- Longitudinal associations between internet access and cognitive decline in older adults.Scientific reports · 2026Article
- Methodological adaptations for applying the Harmonised Cognitive Assessment Protocol diagnostic algorithm in the Northern Ireland Cohort for the Longitudinal Study of Ageing (NICOLA-HCAP).BMC research notes · 2026Article
- Article
- Cohort Profile Update: The Harmonised Cognitive Assessment Protocol sub-study of the Northern Ireland Cohort for the Longitudinal Study of Ageing (NICOLA-HCAP).International journal of epidemiology · 2026Article
- Association of cognitive ability and sleep duration with headache : insights from a Chinese middle-aged and elderly population.BMC public health · 2026Article
- Circadian syndrome, not metabolic syndrome, is a significant predictor of mild cognitive impairment in middle-aged and older adults - The CHARLS survey during 2015-2018.BMC public health · 2026Article
- A multi-stage validation of the C-reactive protein-triglyceride-glucose index for predicting mild cognitive impairment: evidence from clinical and nationwide prospective cohorts.Frontiers in endocrinology · 2026Article
- Early-life nutritional deprivation and multimorbidity in middle- aged and older adults: a longitudinal exploratory mediation analysis of biological aging.Frontiers in nutrition · 2026Article
- Towards cost-effective cognitive impairment diagnosis systems by emulating doctors' reasoning with deep reinforcement learning.BMC geriatrics · 2025Article
- Cognitive and physical functions among Chinese community-dwelling older adults with motoric cognitive risk syndrome: A prospective cohort study.International journal of nursing sciences · 2025Article
- Associations between widowhood status/duration, depression, and cognitive function among community-dwelling Indians age 60 years or older: Exploration of sex and residential factors.Social psychiatry and psychiatric epidemiology · 2025Article
- Own and parental schooling, gender, and cognitive performance based on the Harmonized Cognitive Assessment Protocol (HCAP) among older Chilean adults.The journals of gerontology. Series B, Psychological sciences and social sciences · 2025Article
- Childhood Loneliness and Cognitive Decline and Dementia Risk in Middle-Aged and Older Adults.JAMA network open · 2025Article
8 more citing papers are in PubMed but not listed here.
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Authors and funding
13 authors at 8 institutions in 2 countries.
Funding
Abstract
objectiveTo compare and validate neurocognitive tests in the Harmonized Cognitive Assessment Protocol (HCAP) for the China Health and Retirement Longitudinal Study (CHARLS), and to identify appropriate tests to be administered in future waves of CHARLS.
methodsWe recruited 825 individuals from the CHARLS sample and 766 subjects from hospitals in six provinces and cities in China. All participants were administered the HCAP-neurocognitive tests, and their informants were interviewed regarding the respondents' functional status. Trained clinicians administered the Clinical Dementia Rating scale (CDR) to assess the respondents' cognitive status independently.
resultsThe testing protocol took an average of 58 minutes to complete. Refusal rates for tests of general cognition, episodic memory, and language were less than 10%. All neurocognitive test scores significantly correlated with the CDR global score (correlation coefficients ranged from 0.139 to 0.641). The Mini-Mental State Examination (MMSE), the Health and Retirement Study (HRS) - telephone interview for cognitive status (TICS), community screening instrument for dementia (CSI-D) for respondent, episodic memory and language tests each accounted for more than 20% of the variance in global CDR score (p < 0.001) in bivariate tests. In the CHARLS subsample, age and education were associated with neuropsychological performance across most cognitive domains, and with functional status.
conclusionA brief set of the CHARLS-HCAP neurocognitive tests are feasible and valid to be used in the CHARLS sample and hospital samples. It could be applied in the future waves of the CHARLS study, and it allows estimating the prevalence of dementia in China through the population-based CHARLS.
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