Evidence map›Paper›PMID 31309519›Full record

ReviewInternal and emergency medicine2019

Intravenous immunoglobulin therapy: a snapshot for the internist.

Gianfranco Vitiello, Giacomo Emmi, Elena Silvestri, Gerardo Di Scala, Boaz Palterer, Paola Parronchi

Abstract readReview
PubMed Publisher
In one paragraph

Review in Internal and emergency medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Gianfranco VitielloExperimental and Clinical Medicine Department, University of Firenze, Largo Brambilla 3, 50100, Firenze, Italy. gianfranco.vitiello@unifi.it.ORCID http://orcid.org/0000-0003-4196-3527
Giacomo EmmiExperimental and Clinical Medicine Department, University of Firenze, Largo Brambilla 3, 50100, Firenze, Italy.ORCID http://orcid.org/0000-0001-9575-8321
Elena SilvestriExperimental and Clinical Medicine Department, University of Firenze, Largo Brambilla 3, 50100, Firenze, Italy.
Gerardo Di ScalaExperimental and Clinical Medicine Department, University of Firenze, Largo Brambilla 3, 50100, Firenze, Italy.ORCID http://orcid.org/0000-0002-2245-5589
Boaz PaltererExperimental and Clinical Medicine Department, University of Firenze, Largo Brambilla 3, 50100, Firenze, Italy.ORCID http://orcid.org/0000-0003-2499-8250
Paola ParronchiExperimental and Clinical Medicine Department, University of Firenze, Largo Brambilla 3, 50100, Firenze, Italy.ORCID http://orcid.org/0000-0002-9184-5089
University of Florence · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intravenous immunoglobulins are the cornerstone for the treatment of primary humoral immunodeficiencies and may be used for a great number of other autoimmune, neurological and hematological conditions as well. Given their wide application, the possibility of running across a patient who needs this kind of therapy is becoming increasingly common. Generally, intravenous immunoglobulins are well tolerated. However, numerous adverse reactions ranging from mild to severe have been reported and linked to patient- and product-related factors. For all these reasons, we present herein a comprehensive review of the on- and off-label applications of intravenous immunoglobulins and provide a guide for the internist how to minimize the risk of adverse reactions and manage them.

Indexed as

Administration, IntravenousAutoimmune DiseasesDisease ManagementHumansImmunization, PassiveInternal MedicineAdverse drug reactionsAutoimmune diseasesImmunodeficiencyImmunoglobulinsIVIg

Identifiers

PMID31309519
OpenAlexW2962393687

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.