Evidence map›Paper›PMID 31309465›Full record

ArticleSleep & breathing = Schlaf & Atmung2020

Inner ear function in patients with obstructive sleep apnea.

Xin Li, Wen-Jing Chen, Xiao-Yan Zhang, Si-Chao Liang, Zhen-Ping Guo, Man-Lin Lu, Jing-Ying Ye

Abstract read
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In one paragraph

Article in Sleep & breathing = Schlaf & Atmung, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  4. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Xin LiSchool of Clinical Medicine, Tsinghua University, NO.1, Tsinghua Yuan, Haidian District, Beijing, 100084, China.
Wen-Jing ChenSchool of Clinical Medicine, Tsinghua University, NO.1, Tsinghua Yuan, Haidian District, Beijing, 100084, China.
Xiao-Yan ZhangDepartment of Allergy, The First Hospital of Qinhuangdao city, Qinhuangdao, 066000, Hebei province, China.
Si-Chao LiangDepartment of Otorhinolaryngology, Beijing Tsinghua Changgung Hospital, NO.168, Litang Road, Changping District, Beijing, 102218, China.
Zhen-Ping GuoDepartment of Otorhinolaryngology, Beijing Tsinghua Changgung Hospital, NO.168, Litang Road, Changping District, Beijing, 102218, China.
Man-Lin LuDepartment of Otorhinolaryngology, Beijing Tsinghua Changgung Hospital, NO.168, Litang Road, Changping District, Beijing, 102218, China.
Jing-Ying YeSchool of Clinical Medicine, Tsinghua University, NO.1, Tsinghua Yuan, Haidian District, Beijing, 100084, China. yejy65201347@163.com.

Funding

talents developing programme of Beijing Hospital Authority PX2016031
6 · The paper itself

Abstract

objectiveBecause of their high metabolic activity and low-resting oxygen tension, the organs of the inner ear are vulnerable to hypoxia, a condition that occurs repetitively in obstructive sleep apnea-hypopnea syndrome (OSAHS). The present study aimed to investigate the inner ear function of patients with OSAHS.

methodsA total of 58 patients with OSAHS (116 ears) and 20 adults without OSAHS were enrolled in the present study. The clinical features, such as air-conduction thresholds, auditory brainstem response (ABR, 11 times/s and 51 times/s stimulation rates), and distorted products otoacoustic emission (DPOAE), were evaluated and compared between these two groups.

resultsAir-conduction thresholds at 4 kHz and 8 kHz were higher in patients with OSAHS compared with controls (P < 0.001). At the rate of 11 times per second, biauricular wave I latencies and wave V latencies in the OSAHS group were longer than those in the control group (1.51 ± 0.13 vs. 1.33 ± 0.07 ms, P < 0.001; 5.65 ± 0.23 vs. 5.53 ± 0.23 ms, P = 0.0016). At the rate of 51 times per second, biauricular wave I latencies and wave V latencies in the OSAHS group were longer than those in the control group (1.64 ± 0.12 vs. 1.44 ± 0.06 ms, P = 0.0001; 5.92 ± 0.26 vs. 5.80 ± 0.18 ms, P = 0.0077). However, there was no significant difference in the wave I and wave V interval between these two groups (P = 0.10). DPOAE amplitude was significantly reduced in OSAHS patients, although no hearing loss was observed.

conclusionHigh-frequency hearing loss was detected in adults with severe OSAHS, and wave I latencies and wave V latencies of ABR were prolonged.

Indexed as

AdultAudiometry, Pure-ToneAuditory ThresholdEar, InnerEvoked Potentials, Auditory, Brain StemFemaleHearing Loss, High-FrequencyHumansHypoxiaIschemiaMaleOtoacoustic Emissions, SpontaneousReaction TimeReference ValuesRisk FactorsSleep Apnea, ObstructiveABRDPOAEInner earOSAHS

Identifiers

PMID31309465

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.