Evidence map›Paper›PMID 31309437›Full record

Observational studyInternational ophthalmology2019

Appearance of herpes simplex keratitis on anterior segment optical coherence tomography.

Wael Soliman, Mohamed A Nassr, Khaled Abdelazeem, Ashraf K Al-Hussaini

Abstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in International ophthalmology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.4field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Three-dimensionalFrontiers in medicine · 2023
    Article
  6. Role of AS-OCT in Managing Corneal Disorders.Diagnostics (Basel, Switzerland) · 2022
    Review
  7. Review
  8. Review
  9. Review
  10. Review
  11. Article
  12. Review
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Wael SolimanDepartment of Ophthalmology, Faculty of Medicine, Assiut University, Assiut, Egypt.ORCID http://orcid.org/0000-0002-3548-8267
Mohamed A NassrDepartment of Ophthalmology, Faculty of Medicine, Assiut University, Assiut, Egypt.ORCID http://orcid.org/0000-0002-9186-9654
Khaled AbdelazeemDepartment of Ophthalmology, Faculty of Medicine, Assiut University, Assiut, Egypt. abdelazeem.kh@aun.edu.eg.ORCID http://orcid.org/0000-0002-3437-6984
Ashraf K Al-HussainiDepartment of Ophthalmology, Faculty of Medicine, Assiut University, Assiut, Egypt.
Assiut University · EGAssiut University Hospitals · EGPeterborough City Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo describe the anterior segment AS-OCT findings of herpetic simplex keratitis.

methodsForty-two eyes of 42 patients with proven herpetic keratitis of varying severity were included in this prospective, observational, non-comparative case series study. All subjects underwent ophthalmologic examination and AS-OCT imaging.

resultsTwenty-five of the 42 eyes (59.5%) had sub-epithelial infiltrates. In 11 of these cases, the overlying epithelium appeared intact, but in 14 cases, hydropic changes, heaping, and defects were observed. Seventeen eyes (40.5%) showed stromal involvement: six cases with scar at presentation and one case associated with uveitis. Stromal infiltrates were also seen, in ten cases, as a diffuse or local lentiform or spindle-shaped hyper-reflective area in the stroma.

conclusionHerpetic keratouveitis has characteristic features on AS-OCT images. This study demonstrates that herpetic keratitis also has characteristic AS-OCT features, including sub-epithelial infiltration and specific stromal hyper-reflective patterns. These features are not unique to herpetic keratitis, but AS-OCT imaging may provide useful supplementary information for diagnosing and monitoring herpetic keratitis.

Indexed as

AdultAnterior Eye SegmentCollagenCorneal StromaEpithelium, CornealFemaleHumansKeratitis, HerpeticMaleMiddle AgedProspective StudiesTomography, Optical CoherenceYoung AdultCollagenAnterior segment optical coherence tomographyHerpes simplexHerpetic keratitis

Identifiers

PMID31309437
OpenAlexW2960559827

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.