ArticleInternational journal of colorectal disease2019
Sacral nerve stimulation in slow-transit constipation: effectiveness at 5-year follow-up.
Article in International journal of colorectal disease, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 19 citations in OpenAlex.
- Reframing loss of efficacy in sacral neuromodulation: a neurofunctional service model for coloproctology.Techniques in coloproctology · 2026Article
- Diagnosis and treatment of slow-transit constipation.BMC gastroenterology · 2026Review
- Effects of natural products on functional constipation: analysis of active ingredient and mechanism.Naunyn-Schmiedeberg's archives of pharmacology · 2024Review
- Sacral Neuromodulation for defecation disorders after non oncologic pelvic surgery.International journal of colorectal disease · 2023Article
- Technical and functional outcome after sacral neuromodulation using the "H" technique.Wiener klinische Wochenschrift · 2023Article
- Analysis of the efficacy of biofeedback for faecal incontinence after surgery for anorectal malformation.Annals of medicine · 2022Article
- Comparison of long-term outcome of sacral nerve stimulation for constipation and faecal incontinence with focus on explantation rate, additional visits, and patient satisfaction.Techniques in coloproctology · 2020Article
- Article
- Slow Transit Constipation: Pathophysiological Perspectives and Management Updates.Journal of digestive diseasesReview
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimThe aim of this study is to evaluate the short- and long-term efficacy of sacral nerve stimulation (SNS) for treating slow-transit constipation (STC).
methodThis is a retrospective cohort analysis of the efficacy of SNS in treating patients affected by STC, who previously failed to respond to conservative therapies. Only patients free of concomitant diseases were enrolled in our study. A temporary stimulation lead was initially implanted; patients with a > 50% symptom reduction were eventually deemed eligible for a permanent implant.
resultsThis study enrolled 25 patients who underwent a SNS test stimulation; 21 patients (13 women; median age 32 years) eventually got a permanent implant. The median preoperative Cleveland Clinic Constipation Score (CCCS) was 21 (16-25). Preoperative colorectal transit time recorded a median of 10 markers (7-19) retained in the colorectal tract. At 6-month postoperative follow-up, the total number of markers retained in the colorectal tract decreased to 3 (0-4). The CCCS score improved during the first postoperative year (P < 0.001), but progressively worsened over the longer term. The SF-36 questionnaire showed an improvement in all 8 scales measuring physical and psycho-emotional states; all parameters recorded into the bowel diary also improved. Overall, at 60-month follow up, the overall neuromodulator removal rate was 48%.
conclusionsThe SNS is a minimally invasive surgical procedure that we tested for treating STC. The short-term outcome was promisingly after 6 months; however, there was a declining trend beyond this interval. Thus, the long-term efficacy of SNS needs to be further assessed.
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