ReviewDer Pathologe2020
Complexity of PEComas : Diagnostic approach, molecular background, clinical management.
Review in Der Pathologe, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.
- Gynecologic perivascular epithelioid cell tumors (PEComas): a review of recent evidence.Archives of gynecology and obstetrics · 2024Pooled it
- PEComas: current concepts in diagnosis, molecular pathways, and emerging treatments.The oncologist · 2026Review
- Article
- Review
- Duodenal perforation after retroperitoneal laparoscopic radical nephrectomy for ruptured malignant renal PEComa with spontaneous retroperitoneal hemorrhage: a case report.Frontiers in oncology · 2026Article
- Micronodular PEComa of the appendix: a case report.Frontiers in medicine · 2026Article
- Clinicopathological and molecular features of gynecologic perivascular epithelioid cell tumors: a single-center study.Frontiers in oncology · 2026Article
- Perivascular Epithelioid Cell Neoplasm of the Lung: A Patient Case Report.Case reports in pathology · 2026Article
- Perivascular Epithelioid Cell Tumor of the Lung With a NovelInternational journal of surgical pathology · 2025Article
- Exploring perivascular epithelioid cell tumors (PEComas) in the CNS: insights from two case reports and a comprehensive literature review.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2025Review
- TFE3-rearranged perivascular epithelioid cell tumors of the head and neck with rare fusion partners: clues to the differential diagnosis between benign and malignant tumors.Diagnostic pathology · 2025Article
- Case Report: Malignant perivascular epithelioid cell tumor with aggressive mediastinal invasion and pulmonary metastasis.Frontiers in oncology · 2025Article
- Multiple cell types including melanocytes contribute to elastogenesis in the developing murine aortic valve.Scientific reports · 2024Article
- Unusual PEComa With PRCC :: TFE3 Fusion Mimicking Sinonasal Tract Melanoma.Applied immunohistochemistry & molecular morphology : AIMM · 2024Article
- Perivascular epithelioid cell tumor of the uterus and pelvic cavity.Frontiers in oncology · 2024Article
- Case report: Liver PEComa after kidney transplantation in recipient with tuberous sclerosis complex.Frontiers in oncology · 2024Article
- Perivascular epithelioid cell tumors (PEComas) of the bone and soft tissue: a Japanese Musculoskeletal Oncology Group (JMOG) multi-institutional study.Journal of cancer research and clinical oncology · 2023Article
- Primary Xp11 translocation PEComa of the testis with SFPQ⁃TFE3 rearrangement: a case report and review of the literature.Diagnostic pathology · 2023Review
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- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Perivascular epithelioid cell neoplasms (PEComas) are a family of mesenchymal neoplasms with features of both melanotic and smooth muscle differentiation. PEComa morphology is highly variable and encompasses epithelioid to spindle cells often with clear cytoplasm and prominent nucleoli. Molecularly, most PEComas are defined by a loss of function of the TSC1/TSC2 complex. Additionally, a distinct small subset of PEComas harboring rearrangements of the TFE3 (Xp11) gene locus has been identified. By presenting a series of three case reports with distinct features, we demonstrate diagnostic pitfalls as well as the importance of molecular work-up of PEComas because of important therapeutic consequences.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.