Evidence map›Paper›PMID 31309277›Full record

ArticleEuropean biophysics journal : EBJ2019

Biophysical characterization and molecular phylogeny of human KIN protein.

José Renato Pattaro Júnior, Ícaro Putinhon Caruso, Quirino Alves de Lima Neto, Francisco Ferreira Duarte Junior, Fabiana Dos Santos Rando, Edileusa Cristina Marques Gerhardt, Maria Aparecida Fernandez, Flávio Augusto Vicente Seixas

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In one paragraph

Article in European biophysics journal : EBJ, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

José Renato Pattaro JúniorDepartment of Technology, Universidade Estadual de Maringá-UEM, Av. Ângelo Moreira da Fonseca, 1800, Umuarama, PR, 87506-370, Brazil.
Ícaro Putinhon CarusoDepartment of Physics, Instituto de Biociências, Letras e Ciências Exatas-Universidade Estadual Paulista "Júlio de Mesquita Filho", São José do Rio Preto, SP, Brazil.
Quirino Alves de Lima NetoDepartment of Biotechnology, Genetics and Cell Biology, Universidade Estadual de Maringá, Maringá, PR, Brazil.
Francisco Ferreira Duarte JuniorDepartment of Biotechnology, Genetics and Cell Biology, Universidade Estadual de Maringá, Maringá, PR, Brazil.
Fabiana Dos Santos RandoCenter for Molecular, Structural and Functional Biology, CBM-Research Support Center Complex, Universidade Estadual de Maringá, Maringá, PR, Brazil.
Edileusa Cristina Marques GerhardtDepartment of Biochemistry, Universidade Federal do Paraná, Curitiba, PR, Brazil.
Maria Aparecida FernandezDepartment of Biotechnology, Genetics and Cell Biology, Universidade Estadual de Maringá, Maringá, PR, Brazil.
Flávio Augusto Vicente SeixasDepartment of Technology, Universidade Estadual de Maringá-UEM, Av. Ângelo Moreira da Fonseca, 1800, Umuarama, PR, 87506-370, Brazil. favseixas@uem.br.ORCID http://orcid.org/0000-0002-0117-6919
Universidade Estadual de Maringá · BRUniversidade Estadual Paulista (Unesp) · BRUniversidade Federal do Paraná · BR

Funding

CAPES 001CNPq 305960/2015-6Fundação Araucária 147/14Fundação Araucária 40/16
6 · The paper itself

Abstract

The DNA/RNA-binding KIN protein was discovered in 1989, and since then, it has been found to participate in several processes, e.g., as a transcription factor in bacteria, yeasts, and plants, in immunoglobulin isotype switching, and in the repair and resolution of double-strand breaks caused by ionizing radiation. However, the complete three-dimensional structure and biophysical properties of KIN remain important information for clarifying its function and to help elucidate mechanisms associated with it not yet completely understood. The present study provides data on phylogenetic analyses of the different domains, as well as a biophysical characterization of the human KIN protein (

Indexed as

PhylogenyBiophysical PhenomenaDisulfidesDNA-Binding ProteinsGene Expression RegulationHumansModels, MolecularProtein AggregatesProtein Structure, SecondaryRNA-Binding ProteinsTemperatureDisulfidesDNA-Binding ProteinsKIN protein, humanProtein AggregatesRNA-Binding ProteinsCircular dichroismDSC analysisKIN (Kin17) proteinPhylogenyTumor marker

Identifiers

PMID31309277
OpenAlexW2959681518

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.