Evidence map›Paper›PMID 31309255›Full record

ReviewCancer immunology, immunotherapy : CII2019

Adhering to adhesion: assessing integrin conformation to monitor T cells.

Cécile Gouttefangeas, Juliane Schuhmacher, Stoyan Dimitrov

Abstract readReview
In one paragraph

Review in Cancer immunology, immunotherapy : CII, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Cécile GouttefangeasDepartment of Immunology, Interfaculty Institute for Cell Biology, Eberhard Karls University, Auf der Morgenstelle 15, 72076, Tübingen, Germany. cecile.gouttefangeas@uni-tuebingen.de.ORCID http://orcid.org/0000-0002-6410-2378
Juliane SchuhmacherDepartment of Immunology, Interfaculty Institute for Cell Biology, Eberhard Karls University, Auf der Morgenstelle 15, 72076, Tübingen, Germany.
Stoyan DimitrovInstitute of Medical Psychology and Behavioral Neurobiology, Eberhard Karls University, Otfried-Müller Straße 25, 72076, Tübingen, Germany. stoyan.dimitrov@uni-tuebingen.de.ORCID https://orcid.org/0000-0002-1184-1441

Funding

Bundesministerium für Bildung und Forschung (DE) 01GI0925Deutsche Forschungsgemeinschaft SFB685
6 · The paper itself

Abstract

Monitoring T cells is of major importance for the development of immunotherapies. Recent sophisticated assays can address particular aspects of the anti-tumor T-cell repertoire or support very large-scale immune screening for biomarker discovery. Robust methods for the routine assessment of the quantity and quality of antigen-specific T cells remain, however, essential. This review discusses selected methods that are commonly used for T-cell monitoring and summarizes the advantages and limitations of these assays. We also present a new functional assay, which specifically detects activated β

Indexed as

AntigensBiomarkersCell AdhesionHumansImmunotherapyIntegrin alpha2T-LymphocytesAntigensBiomarkersIntegrin alpha2AdhesionFunctionImmunomonitoringImmunotherapyPIVAC 2018T cell

Identifiers

PMID31309255
PMCPMC11028104

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.