ArticleEuropean journal of trauma and emergency surgery : official publication of the European Trauma Society2021
Risk factors for postoperative morbidity following appendectomy in the elderly: a nationwide prospective cohort study.
Article in European journal of trauma and emergency surgery : official publication of the European Trauma Society, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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14 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.
- EAES rapid guideline: appendicitis in the elderly.Surgical endoscopy · 2021Guideline
- Laparoscopic appendectomy as the gold standard: What role remains for open surgery, conversion, and disease severity? : An analysis of 32,000 cases with appendicitis in Germany.World journal of emergency surgery : WJES · 2025Observational
- Article
- Influence of sarcopenia and frailty in the management of elderly patients with acute appendicitis.World journal of clinical cases · 2024Article
- Acute Appendicitis in the Elderly: A Nationwide Retrospective Analysis.Journal of clinical medicine · 2024Article
- The Emergency Surgery Frailty Index (EmSFI) in Elderly Patients with Acute Appendicitis: An External Validation of Prognostic Score.World journal of surgery · 2023Observational
- Risk Factors for Conversion from Laparoscopic to Open Appendectomy.Journal of clinical medicine · 2023Article
- Acute appendicitis over the age of 50: The evaluation of the impact of clinical variables on operative and post-operative outcomes.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2022Article
- Clinical-pathological features and treatment of acute appendicitis in the very elderly: an interim analysis of the FRAILESEL Italian multicentre prospective study.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2022Article
- Development and Validation of a Clinical Prediction Model for Complicated Appendicitis in the Elderly.Frontiers in surgery · 2022Article
- Acute Appendicitis in the Elderly: A Literature Review on an Increasingly Frequent Surgical Problem.Geriatrics (Basel, Switzerland) · 2021Review
- The Emergency Surgery Frailty Index (EmSFI): development and internal validation of a novel simple bedside risk score for elderly patients undergoing emergency surgery.Aging clinical and experimental research · 2021Article
- Experimental evidence and network pharmacology-based analysis reveal the molecular mechanism of Tongxinluo capsule administered in coronary heart diseases.Bioscience reports · 2020Article
- The use of emergency laparoscopy for acute abdomen in the elderly: the FRAILESEL Italian Multicenter Prospective Cohort Study.Updates in surgery · 2020Article
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10 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundA limited number of studies investigating perioperative risk factors associated with emergency appendectomy in elderly patients have been published to date. Whether older age may be associated with poorer outcomes following appendectomy is still a matter of debate. The primary aim of this study was to determine the predictors of postoperative morbidity following appendectomy in patients aged ≥ 65 years.
methodsData regarding all elderly patients who underwent emergency appendectomy from January 2017 to June 2018 admitted 36 Italian surgical departments were prospectively collected and analyzed. Baseline demographics and perioperative variables were evaluated. Uni- and multivariate analyses adjusted for differences between groups were carried out to determine possible predictors of adverse outcomes after appendectomy.
resultsBetween January 2017 and June 2018, 135 patients aged ≥ 65 years with a diagnosis of AA met the study inclusion criteria. Twenty-six patients (19.3%) were diagnosed with some type of postoperative complication. Decreasing the preoperative hemoglobin level showed a statistically significant association with postoperative complications (OR 0.77, CI 0.61-0.97, P = 0.03). Preoperative creatinine level (P = 0.02, OR 2.04, CI 1.12-3.72), and open appendectomy (P = 0.03, OR 2.67, CI 1.11-6.38) were significantly associated with postoperative morbidity. After adjustment, the only independent predictor of postoperative morbidity was preoperative creatinine level (P = 0.04, OR 2.01, CI 1.05-3.89).
conclusionsIn elderly patients with AA, perioperative risk assessment in the emergency setting must be as accurate as possible to identify modifiable risk factors that can be addressed before surgery, such as preoperative hemoglobin and creatinine levels.
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