ArticleScience advances2019
Optimal transport and colossal ionic mechano-conductance in graphene crown ethers.
Article in Science advances, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Diffusive to Barrier-Limited Transition in the Aqueous Ion Transport through Nanoporous 2D Materials.The journal of physical chemistry. B · 2025Article
- Article
- Molecular dynamics simulations reveal concentration-dependent blockage of graphene quantum dots to water channel protein openings.Scientific reports · 2024Article
- Designing artificial ion channels with strict KNational science review · 2023Article
- Fluids and Electrolytes under Confinement in Single-Digit Nanopores.Chemical reviews · 2023Review
- Nonlinear electrohydrodynamic ion transport in graphene nanopores.Science advances · 2022Article
- Rational ion transport management mediated through membrane structures.Exploration (Beijing, China) · 2021Review
- Prospects of Observing Ionic Coulomb Blockade in Artificial Ion Confinements.Entropy (Basel, Switzerland) · 2020Article
- Diffusion Limitations and Translocation Barriers in Atomically Thin Biomimetic Pores.Entropy (Basel, Switzerland) · 2020Article
- Colloquium: Ionic phenomena in nanoscale pores through 2D materials.Reviews of modern physics · 2019Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Biological ion channels balance electrostatic and dehydration effects to yield large ion selectivity alongside high transport rates. These macromolecular systems are often interrogated through point mutations of their pore domain, limiting the scope of mechanistic studies. In contrast, we demonstrate that graphene crown ether pores afford a simple platform to directly investigate optimal ion transport conditions, i.e., maximum current densities and selectivity. Crown ethers are known for selective ion adsorption. When embedded in graphene, however, transport rates lie below the drift-diffusion limit. We show that small pore strains (1%) give rise to a colossal (100%) change in conductance. This process is electromechanically tunable, with optimal transport in a primarily diffusive regime, tending toward barrierless transport, as opposed to a knock-on mechanism. These observations suggest a novel setup for nanofluidic devices while giving insight into the physical foundation of evolutionarily optimized ion transport in biological pores.
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Registered trials
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