ArticleSSM - population health2019
Free trade and opioid overdose death in the United States.
Article in SSM - population health, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 21 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 64 citations in OpenAlex.
- Pooled it
- Social and economic determinants of drug overdose deaths: a systematic review of spatial relationships.Social psychiatry and psychiatric epidemiology · 2024Pooled it
- Coverage Limitations for Use of Urine Drug Testing in a State Medicaid Program.JAMA network open · 2026Article
- What Drives Risky Prescription Opioid Use?: Evidence from Migration.The quarterly journal of economics · 2025Article
- Geography And Fentanyl: Explaining The Disproportionate Rise In Opioid Overdose Deaths Among Black Americans.Health affairs (Project Hope) · 2025Article
- Changes in the association between county industrial composition and working-age mortality from 2000 to 2022.SSM - population health · 2025Article
- Revealed Comparative Disadvantage of Infants: Exposure to NAFTA and Birth Outcomes.Journal of international economics · 2025Article
- Black Americans' Drug Mortality Increases and Local Employment Opportunities, 2010‒2021.American journal of public health · 2024Article
- Association of globalization with the burden of opioid use disorders 2019. A country-level analysis using targeted maximum likelihood estimation.Globalization and health · 2023Article
- Characteristics of post-overdose outreach programs and municipal-level opioid overdose in Massachusetts.The International journal on drug policy · 2023Article
- State-level homelessness and drug overdose mortality: Evidence from US panel data.Drug and alcohol dependence · 2023Article
- Narrative minireview of the spatial epidemiology of substance use disorder in the United States: Who is at risk and where?World journal of clinical cases · 2023Review
- The rise of illicit fentanyls, stimulants and the fourth wave of the opioid overdose crisis.Current opinion in psychiatry · 2021Review
- Perceptions of Diseases of Despair by Members of Rural and Urban High-Prevalence Communities: A Qualitative Study.JAMA network open · 2021Article
- A Critical Review of the Social and Behavioral Contributions to the Overdose Epidemic.Annual review of public health · 2021Review
- Foundations of complexity economics.Nature reviews. Physics · 2021Review
- Geographical Aspects of Recent Trends in Drug-Related Deaths, with a Focus on Intra-National Contextual Variation.International journal of environmental research and public health · 2020Article
- The Relative Economy and Drug Overdose Deaths.Epidemiology (Cambridge, Mass.) · 2020Article
- Epidemiological and geospatial profile of the prescription opioid crisis in Ohio, United States.Scientific reports · 2020Article
- Association Between Automotive Assembly Plant Closures and Opioid Overdose Mortality in the United States: A Difference-in-Differences Analysis.JAMA internal medicine · 2020Article
Corrections and comments
- Erratum issued
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
Opioid overdose deaths in the U.S. rose dramatically after 1999, but also exhibited substantial geographic variation. This has largely been explained by differential availability of prescription and non-prescription opioids, including heroin and fentanyl. Recent studies explore the underlying role of socioeconomic factors, but overlook the influence of job loss due to international trade, an economic phenomenon that disproportionately harms the same regions and demographic groups at the heart of the opioid epidemic. We used OLS regression and county-year level data from the Centers for Disease Controls and the Department of Labor to test the association between trade-related job loss and opioid-related overdose death between 1999 and 2015. We find that the loss of 1000 trade-related jobs was associated with a 2.7 percent increase in opioid-related deaths. When fentanyl was present in the heroin supply, the same number of job losses was associated with a 11.3 percent increase in opioid-related deaths.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.