Evidence map›Paper›PMID 31309133›Full record

ReviewEuropean journal of radiology open2019

"CHOICES": An acronym to aid in delineating potential causes of non-metabolic, non-infectious acute toxic leukoencephalopathy.

Yasemin Koksel, Can Ozutemiz, Jeffrey Rykken, Frederick Ott, Zuzan Cayci, Mark Oswood, Alexander M McKinney

Erratum issuedAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in European journal of radiology open, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Yasemin KokselDepartment of Radiology, Division of Neuroradiology, University of Minnesota Medical Center, Minneapolis, MN, USA.
Can OzutemizDepartment of Radiology, Division of Neuroradiology, University of Minnesota Medical Center, Minneapolis, MN, USA.
Jeffrey RykkenDepartment of Radiology, Division of Neuroradiology, University of Minnesota Medical Center, Minneapolis, MN, USA.
Frederick OttDepartment of Radiology, Division of Neuroradiology, University of Minnesota Medical Center, Minneapolis, MN, USA.
Zuzan CayciDepartment of Radiology, Division of Neuroradiology, University of Minnesota Medical Center, Minneapolis, MN, USA.
Mark OswoodDepartment of Radiology, Division of Neuroradiology Hennepin Healthcare Medical Center, Minneapolis, MN, USA.
Alexander M McKinneyDepartment of Radiology, Division of Neuroradiology, University of Minnesota Medical Center, Minneapolis, MN, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo describe non-metabolic, non-infectious etiologies of acute toxic leukoencephalopathy (ATL) on DWI MRI, and provide a useful acronym to remember them. MATERIAL AND

methodsOur PACS archive was reviewed, yielding 185 patients with suspected ATL per MRI reports and clinical follow up; infectious or metabolic causes were excluded. RESULT/DISCUSSION: The 87 included non-infectious, non-metabolic ATL patients' etiologies are represented by the acronym 'CHOICES': chemotherapy ('C',n = 34); heroin-induced ('H',n = 6), opioid analogues ('O',n = 14); immunosuppressant ('I',n = 11) or imidazole (n = 2); cocaine ('C',n = 1); environmental or ethanol abuse ('E',n = 5), splenial lesions ('S',n = 9), and 'other' (n = 5).

conclusionThe "CHOICES" acronym delineates various toxic etiologies of ATL.

Indexed as

Acute toxic leukoencephalopathyADEM, Acute disseminated encephalomyelitisAEDs, Anti-epileptic drugsAHE, Acute Hepatic/Hyperammonemic EncephalopathyAHL, Acute hemorrhagic leukoencephalitisATL, Acute toxic leukoencephalopathyCO, Carbon monoxideDiffusion-Weighted imagingEPM, Extrapontine myelinolysisEtOH, EthanolHIE, Hypoxic-ischemic encephalopathyLE, leukoencephalopathyMBD, Marchiafava-Bignami DiseaseMERS, Mild encephalitis/encephalopathy with reversible splenial lesionNAWM, Normal-appearing white matterODS, Osmotic demyelination syndromePeriventricular white matterPML, Progressive multifocal leukoencephalopathyPRES, Posterior reversible encephalopathy syndromePVWM, Periventricular white matterRIS, Radiology information systemRSL, Reversible splenial lesions

Identifiers

PMID31309133
PMCPMC6607360

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.