Evidence map›Paper›PMID 31309120›Full record

ReviewBioMed research international2019

Noncoding RNAs Act as Tumor-Derived Molecular Components in Inducing Premetastatic Niche Formation.

Zhedong Zhang, Jiao Qiao, Dafang Zhang, Weihua Zhu, Jiye Zhu, Xisheng Leng, Shu Li

RetractedAbstract readReviewRetracted Publication
In one paragraph

Review in BioMed research international, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Zhedong ZhangDepartment of Hepatobiliary Surgery, Peking University People's Hospital, Beijing, 100044, China.ORCID 0000-0002-1868-2826
Jiao QiaoDepartment of Nephrology, Shandong Provincial Hospital Affiliated to Shandong University, Shandong, 250021, China.
Dafang ZhangDepartment of Hepatobiliary Surgery, Peking University People's Hospital, Beijing, 100044, China.
Weihua ZhuDepartment of Hepatobiliary Surgery, Peking University People's Hospital, Beijing, 100044, China.ORCID 0000-0003-2698-3423
Jiye ZhuDepartment of Hepatobiliary Surgery, Peking University People's Hospital, Beijing, 100044, China.ORCID 0000-0001-5406-2715
Xisheng LengDepartment of Hepatobiliary Surgery, Peking University People's Hospital, Beijing, 100044, China.ORCID 0000-0001-9822-718X
Shu LiDepartment of Hepatobiliary Surgery, Peking University People's Hospital, Beijing, 100044, China.ORCID 0000-0002-0080-3562

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer metastasis has been demonstrated as it is the culmination of a cascade of priming steps. Increasing evidence has shown that tumor-derived molecular components (TDMCs) are known as extra cellular vesicle and nonvesicle factors and serve as versatile intercellular communication vehicles which can mediate signaling in the tumor microenvironment while creating the premetastatic niche. Noncoding RNAs (ncRNAs) as one of the TDMCs have been proved in participating in the formation of the premetastatic niche. Understanding the premetastatic niche formation mechanisms through TDMCs, especially ncRNAs may open a new avenue for cancer metastasis therapeutic strategies. In this review, recent findings regarding ncRNAs function were summarized, and then the interaction with the premetastatic niche formation was studied, which highlight the potential of using ncRNAs for cancer diagnosis and therapeutic effect.

Indexed as

Cell CommunicationSignal TransductionTumor MicroenvironmentAnimalsExtracellular VesiclesHumansNeoplasm MetastasisNeoplasmsRNA, NeoplasmRNA, UntranslatedRNA, NeoplasmRNA, Untranslated

Identifiers

PMID31309120
PMCPMC6594336

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.