Evidence map›Paper›PMID 31309105›Full record

ArticleBioMed research international2019

Cytokine Regulation from Human Peripheral Blood Leukocytes Cultured

Jefferson Muniz de Lima, Edlainne Pinheiro Ferreira, Roberta Ferreti Bonan, David Nascimento Silva-Teixeira, Luiz Ricardo Goulart, Joelma Rodrigues de Souza, Eliton Souto de Medeiros, Paulo Rogério Ferreti Bonan, Lúcio Roberto Cançado Castellano

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Jefferson Muniz de LimaHuman Immunology Research and Education Group-GEPIH, Escola Técnica de Saúde da UFPB, Universidade Federal da Paraíba, João Pessoa, Brazil.ORCID https://orcid.org/0000-0002-9712-1102
Edlainne Pinheiro FerreiraHuman Immunology Research and Education Group-GEPIH, Escola Técnica de Saúde da UFPB, Universidade Federal da Paraíba, João Pessoa, Brazil.ORCID https://orcid.org/0000-0001-9907-1850
Roberta Ferreti BonanHuman Immunology Research and Education Group-GEPIH, Escola Técnica de Saúde da UFPB, Universidade Federal da Paraíba, João Pessoa, Brazil.ORCID https://orcid.org/0000-0001-8737-6032
David Nascimento Silva-TeixeiraInstitute of Health Sciences, Department of Clinical Medicine, Universidade Federal do Triângulo Mineiro Federal, Uberaba, Brazil.
Luiz Ricardo GoulartLaboratory of Nanobiotechnology, Institute of Genetics and Biochemistry, Universidade Federal de Uberlandia, Uberlandia, Brazil.ORCID https://orcid.org/0000-0002-1803-4861
Joelma Rodrigues de SouzaHuman Immunology Research and Education Group-GEPIH, Escola Técnica de Saúde da UFPB, Universidade Federal da Paraíba, João Pessoa, Brazil.
Eliton Souto de MedeirosMaterials and Biosystems Laboratory, Universidade Federal da Paraíba, João Pessoa, Brazil.
Paulo Rogério Ferreti BonanHuman Immunology Research and Education Group-GEPIH, Escola Técnica de Saúde da UFPB, Universidade Federal da Paraíba, João Pessoa, Brazil.ORCID https://orcid.org/0000-0002-4449-4343
Lúcio Roberto Cançado CastellanoHuman Immunology Research and Education Group-GEPIH, Escola Técnica de Saúde da UFPB, Universidade Federal da Paraíba, João Pessoa, Brazil.ORCID https://orcid.org/0000-0003-0851-5298
Universidade Federal da Paraíba · BRUniversidade Federal do Triângulo Mineiro · BRUniversity of California Davis Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bioactive glasses (BG) applications include tissue engineering for bone regeneration, coating for implants, and scaffolds for wound healing. BG can be conjugated to ions like silver, which might add some antimicrobial properties to this biomaterial. The immunomodulatory activity of ion-doped bioactive glasses particles was not investigated before. The aim of this work was to evaluate the cytotoxic and immunomodulatory effect of BG and silver-doped bioactive glass (BGAg) in human peripheral blood cells. BG and BGAg samples belonging to the system 58SiO

Indexed as

Biocompatible MaterialsCell LineCell SurvivalCytokinesGlassHumansInflammationLeukocytes, MononuclearReactive Oxygen SpeciesSilverTissue EngineeringWound HealingBiocompatible MaterialsCytokinesReactive Oxygen SpeciesSilver

Identifiers

PMID31309105
PMCPMC6594341
OpenAlexW2953223167

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.