ReviewMediterranean journal of hematology and infectious diseases2019
Sickle Cell Disease and Pregnancy.
Review in Mediterranean journal of hematology and infectious diseases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
51 citing papers in PubMed, 2 syntheses or guidelines pooled it, 98 citations in OpenAlex.
- Acute pain episodes, acute chest syndrome, and pulmonary thromboembolism in pregnancy.Hematology. American Society of Hematology. Education Program · 2022Pooled it
- Pregnancy in the Sickle Cell Disease and Fetomaternal Outcomes in Different Sickle cell Genotypes: A Systematic Review and Meta-Analysis.Ethiopian journal of health sciences · 2022Pooled it
- The acceptability and feasibility of a randomised controlled trial of serial prophylactic exchange blood transfusion versus usual care in pregnant women with sickle cell disease: a qualitative study.BMC pregnancy and childbirth · 2026Trial
- Prophylactic exchange transfusion in sickle cell disease pregnancy: a TAPS2 feasibility randomized controlled trial.Blood advances · 2024Trial
- Burden of sickle cell disease among pregnant women in central India.The Indian journal of medical research · 2026Article
- Comment on: Managing sickle cell disease and related complications in pregnancy: results of an international Delphi panel.BMC pregnancy and childbirth · 2026Article
- Gynecologic and Reproductive Health in Patients with Sickle Cell Disease: Underrecognized Challenges and Care Management Opportunities.Journal of clinical medicine · 2026Review
- Sickle cell disease and maternity care: A qualitative synthesis of women's and health providers experiences.PloS one · 2026Article
- Impact of sickle cell anaemia on reproductive health: a narrative review.Reproductive health · 2025Review
- Racial and Ethnic Disparities in the Incidence and Treatment of Urinary Tract Infection During Pregnancy.Journal of women's health (2002) · 2025Article
- New WHO recommendations on the management of sickle-cell disease in pregnancy.Pregnancy (Hoboken, N.J.) · 2025Article
- Antenatal medication management for women with sickle-cell disease: A systematic review.Pregnancy (Hoboken, N.J.) · 2025Review
- Interpregnancy management for women with sickle cell disease: A systematic review.Pregnancy (Hoboken, N.J.) · 2025Review
- Timing and mode of birth for women with sickle cell disease: A systematic review.Pregnancy (Hoboken, N.J.) · 2025Review
- Prophylactic vs therapeutic blood transfusions impact on pregnant sickle cell patients.Pakistan journal of medical sciences · 2025Article
- Histomorphology of placentae of women with sickle cell disease during pregnancy - A case control study.PloS one · 2025Article
- Prevalence of sickle cell anemia in Africa: A protocol for a meta-analysis of existing studies.PloS one · 2025Article
- Burden of hemoglobinopathies and hemolytic anemias in the World Health Organization African region, 2000-2021: Findings from the Global Burden of Disease 2021 study.PLOS global public health · 2025Article
- Intimate partner violence related to disclosure of sickle cell disease during pregnancy: evidence from the sickle cell belt of central India.Frontiers in global women's health · 2025Article
- The Heat Is On: Climate Change Implications for Pregnant Women with Sickle Cell Disease.Women's health reports (New Rochelle, N.Y.) · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Sickle cell disease (SCD) is the most common inherited hemoglobinopathy and is associated with increased risk of complications and early mortality. Nowadays, with improved health care facilities, antibiotic prophylaxis, vaccination, and availability of drugs like hydroxyurea, the life expectancy of SCD patients has improved. More women are reaching reproductive age group and are expressing their desire to reproduce. Though SCD adversely affects pregnancy, leading to increased incidence of maternal and perinatal complications like pre-eclampsia, preterm labor, IUGR, abortions etc., adequate care throughout pregnancy ensures a better outcome. Also, recent advancements in the fields of prenatal diagnosis and preimplantation genetic diagnosis, help couples suffering from SCD to have a healthy baby. This paper focuses on the effects of SCD on pregnancy outcomes and effective management of complications during pregnancy, also comparing maternal and perinatal outcomes in studies conducted in different countries. The second part of the paper summarizes pregnancy management in SCD for better maternal and fetal outcomes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.