Evidence map›Paper›PMID 31308818›Full record

ArticleJournal of ginseng research2019

Impact of

Luping Zhou, Lulu Chen, Yaqin Wang, Jie Huang, Guoping Yang, Zhirong Tan, Yicheng Wang, Jianwei Liao, Gan Zhou, Kai Hu and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of ginseng research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Journal of ginseng research · 2026
    Review
  2. Ginsenosides fromJournal of ginseng research · 2026
    Review
  3. Article
  4. Review
  5. Review
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Luping ZhouDepartment of Clinical Pharmacology, Xiangya Hospital, Central South University, Changsha, China.
Lulu ChenDepartment of Clinical Pharmacology, Xiangya Hospital, Central South University, Changsha, China.
Yaqin WangDepartment of Clinical Pharmacology, Xiangya Hospital, Central South University, Changsha, China.
Jie HuangCenter of Clinical Pharmacology, The Third Xiangya Hospital, Central South University, Changsha, China.
Guoping YangCenter of Clinical Pharmacology, The Third Xiangya Hospital, Central South University, Changsha, China.
Zhirong TanDepartment of Clinical Pharmacology, Xiangya Hospital, Central South University, Changsha, China.
Yicheng WangDepartment of Clinical Pharmacology, Xiangya Hospital, Central South University, Changsha, China.
Jianwei LiaoDepartment of Clinical Pharmacology, Xiangya Hospital, Central South University, Changsha, China.
Gan ZhouDepartment of Clinical Pharmacology, Xiangya Hospital, Central South University, Changsha, China.
Kai HuDepartment of Neurology, Xiangya Hospital, Central South University, Changsha, China.
Zhenyu LiDepartment of Cardiology, Xiangya Hospital, Central South University, Changsha, China.
Dongsheng OuyangDepartment of Clinical Pharmacology, Xiangya Hospital, Central South University, Changsha, China.
Central South University · CNXiangya Hospital Central South University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGinsenoside compound K (CK) is a promising drug candidate for rheumatoid arthritis. This study examined the impact of polymorphisms in

methodsForty-two targeted variants in seven genes were genotyped in 54 participants using Sequenom MassARRAY system to investigate their association with major pharmacokinetic parameters of CK and its metabolite 20(S)-protopanaxadiol (PPD). Subsequently, molecular docking was simulated using the AutoDock Vina program.

resultsCONLUSION:

Indexed as

Genetic polymorphismsGinsenoside compound KPharmacokineticsTransporters

Identifiers

PMID31308818
PMCPMC6606825
OpenAlexW2800055155

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.