Evidence map›Paper›PMID 31308752›Full record

ArticleCancer management and research2019

Modified Glasgow prognostic score as a prognostic factor for renal cell carcinomas: a systematic review and meta-analysis.

Xu Hu, Yan Wang, Wei-Xiao Yang, Wei-Chao Dou, Yan-Xiang Shao, Xiang Li

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Article in Cancer management and research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 7 of them syntheses that pooled it.

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23citing papers in PubMed, 7 pooled it
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 7 syntheses or guidelines pooled it.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Xu Hu *West China School of Medicine/West China Hospital, Sichuan University, Chengdu 610041, People's Republic of China.
Yan Wang *West China School of Medicine/West China Hospital, Sichuan University, Chengdu 610041, People's Republic of China.
Wei-Xiao Yang *West China School of Medicine/West China Hospital, Sichuan University, Chengdu 610041, People's Republic of China.
Wei-Chao DouWest China School of Medicine/West China Hospital, Sichuan University, Chengdu 610041, People's Republic of China.
Yan-Xiang ShaoWest China School of Medicine/West China Hospital, Sichuan University, Chengdu 610041, People's Republic of China.
Xiang LiDepartment of Urology, West China Hospital, West China Medical School, Sichuan University, Chengdu 610041, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe modified Glasgow prognostic score (mGPS), a combination of C-reactive protein (CRP) and albumin levels, reflects systemic inflammation and nutritional status. This score has been shown to have prognosis value for various tumors. In the present study, we evaluated the prognostic value of mGPS for patients with renal cell carcinoma (RCC).

methodsLiterature search was conducted based on PubMed, Embase, and Cochrane Central Register of Controlled Trials up to December 2018. We pooled HRs and 95% CIs to evaluate the correlation between mGPS and survival in patients with RCC.

resultsTwelve studies comprising 2,391 patients were included in the present study for quantitative synthesis. Our studies demonstrated that higher mGPS was significantly correlated to poor overall survival (HR=4.31; 95%CI, 2.78-6.68;

conclusionmGPS could serve as a predictive tool for the survival of patients with RCC. In the different subgroups, the results are also consistent with previous results. In conclusion, pretreatment higher mGPS is associated with poorer survival in patients with RCC. Further external validations are necessary to strengthen this concept.

Indexed as

meta-analysismodified Glasgow prognostic scoreprognosisrenal cell carcinoma

Identifiers

PMID31308752
PMCPMC6613602

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.