Evidence map›Paper›PMID 31308749›Full record

ArticleCancer management and research2019

M2 macrophage infiltration into tumor islets leads to poor prognosis in non-small-cell lung cancer.

Lili Cao, Xiaofang Che, Xueshan Qiu, Zhi Li, Bowen Yang, Shuo Wang, Kezuo Hou, Yibo Fan, Xiujuan Qu, Yunpeng Liu

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Cancer management and research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05019235 (Study of the Association Between Tumor Microenvironment Macrophages and Treatment Response in Squamous Cell Carcinoma of the Anal Canal), which is not on this map. Cited by 87 papers.

0numbers the graph read from it
0cells of the map it votes in
87citing papers in PubMed
6.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05019235 unknown statusnot on this mapstarted 2021, after this paper: background citation

Study of the Association Between Tumor Microenvironment Macrophages and Treatment Response in Squamous Cell Carcinoma of the Anal Canal

TypeobservationalSponsorFondation Hôpital Saint-JosephRan2021 to 2023Enrolled154ConditionsSquamous Cell Carcinoma
3 · Its place in the literature

Who cites it

87 citing papers in PubMed, 141 citations in OpenAlex.

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  9. EGFR: New Insights on Its Activation and Mutation in Tumor and Tumor Immunotherapy.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
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27 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Lili Cao *Department of Medical Oncology, The First Hospital of China Medical University, Shenyang 110001, People's Republic of China.
Xiaofang Che *Department of Medical Oncology, The First Hospital of China Medical University, Shenyang 110001, People's Republic of China.
Xueshan QiuDepartment of Pathology, College of Basic Medical Sciences of China Medical University, Shenyang 110001, People's Republic of China.
Zhi LiDepartment of Medical Oncology, The First Hospital of China Medical University, Shenyang 110001, People's Republic of China.
Bowen YangDepartment of Medical Oncology, The First Hospital of China Medical University, Shenyang 110001, People's Republic of China.
Shuo WangDepartment of Medical Oncology, The First Hospital of China Medical University, Shenyang 110001, People's Republic of China.
Kezuo HouDepartment of Medical Oncology, The First Hospital of China Medical University, Shenyang 110001, People's Republic of China.
Yibo FanDepartment of Medical Oncology, The First Hospital of China Medical University, Shenyang 110001, People's Republic of China.
Xiujuan QuDepartment of Medical Oncology, The First Hospital of China Medical University, Shenyang 110001, People's Republic of China.
Yunpeng LiuDepartment of Medical Oncology, The First Hospital of China Medical University, Shenyang 110001, People's Republic of China.
First Hospital of China Medical University · CNChina Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

macrophagemicroenvironmentnon-small-cell lung cancerPD-L1polarizationprognosis

Identifiers

PMID31308749
PMCPMC6613613
OpenAlexW2955930663

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.