Evidence map›Paper›PMID 31308734›Full record

ArticleJournal of pain research2019

Ultrasound-guided subcostal transversus abdominis plane block with liposomal bupivacaine compared to bupivacaine infiltration for patients undergoing robotic-assisted and laparoscopic hysterectomy: a prospective randomized study.

Jacob Hutchins, Peter Argenta, Aaron Berg, Jason Habeck, Alexander Kaizer, Melissa A Geller

2 registry-linked trialsOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of pain research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 15 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 3 pooled it
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05224089 phase4recruitingnot on this mapstarted 2022, after this paper: background citation

Bilateral Mid-Abdominal Transverse Abdominis Plane and Rectus Sheath Blocks Comparing The Use of Liposomal Bupivacaine/Bupivacaine vs. Regular Bupivacaine in Laparoscopic Colectomy Procedures.

TypeinterventionalSponsorHartford HospitalRan2022 to 2026Enrolled114ConditionsBowel DiseaseArmsLiposomal Bupivicaine/Bupivacaine Admixture, Bupivacaine HCL
NCT05763667 phase3completednot on this mapstarted 2024, after this paper: background citation

A Randomized, Controlled, Observer-blinded Pilot Trial of Laparoscopic Large Volume, Multisite Transversus Abdominal Plane (TAP) Block With Liposomal Bupivacaine in Patients Undergoing Minimally Invasive Hysterectomy for Endometrial Cancer

TypeinterventionalSponsorTufts Medical CenterRan2024 to 2024Enrolled15ConditionsPost Operative Pain, Gynecologic CancerArmsLiposomal bupivacaine, Bupivacain
3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 3 syntheses or guidelines pooled it, 29 citations in OpenAlex.

  1. Pooled it
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  7. Laparoscopic Posterior Versus Lateral Transversus Abdominis Plane Block in Gynecology.JSLS : Journal of the Society of Laparoendoscopic Surgeons
    Trial
  8. Article
  9. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Jacob HutchinsDepartment of Anesthesiology, University of Minnesota, Minneapolis, MN, USA.
Peter ArgentaDepartment of Obstetrics, Gynecology and Women's Health, Minneapolis, MN, USA.
Aaron BergDepartment of Anesthesiology, University of Minnesota, Minneapolis, MN, USA.
Jason HabeckDepartment of Anesthesiology, University of Minnesota, Minneapolis, MN, USA.
Alexander KaizerDepartment of Biostatistics and Informatics, Colorado School of Public Health, University of Colorado, Aurora, CO, USA.
Melissa A GellerDepartment of Obstetrics, Gynecology and Women's Health, Minneapolis, MN, USA.
University of Minnesota · USWomen’s Health Care · USColorado School of Public Health · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo determine if a transversus abdominis plane (TAP) block with liposomal bupivacaine reduces total postoperative opioid use in the first 72 hrs following laparoscopic or robotic hysterectomy compared to port-site infiltration with 0.25% bupivacaine.

methodsPatients received either a true TAP block procedure with 266 mg liposomal bupivacaine and 50 mg of 0.25% bupivacaine and sham port infiltration or sham TAP block procedure with true port-site infiltration with 100-125 mg of 0.25% bupivacaine. All patients had a standardized, scheduled, non-opioid pain management plan. The primary outcome was total IV morphine equivalents used in the first 72 hrs following surgery. Secondary outcomes included assessment of postoperative pain over the study period and quality of recovery measures.

resultsPatients undergoing TAP blockade required fewer total opioid equivalents during the observation period than patients allocated to infiltration (median 21 versus 25 mg IV Morphine equivalents,

conclusionTAP blockade reduced the requirement for opioid pain medication in the first 72 hrs after surgery, had more patients opioid free at 72 hrs, and improved patients' quality of their recovery.

Indexed as

acute painliposome bupivacaineregional painTAP block

Identifiers

PMID31308734
PMCPMC6614855
OpenAlexW2955507953

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.