ArticleClinical interventions in aging2019
Association between inflammation-based prognostic scores and in-hospital outcomes in elderly patients with acute myocardial infarction.
Article in Clinical interventions in aging, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Association between prognostic nutritional index and the clinical outcomes of patients with acute myocardial infarction: a systematic review and meta-analysis.Frontiers in cardiovascular medicine · 2025Pooled it
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- Inflammation-based Scores in Patients With Pheochromocytoma.The Journal of clinical endocrinology and metabolism · 2025Article
- Comparative Prognostic Accuracy of Clinical and Inflammation- or Nutrition-Based Scores in Older Adults with Community-Acquired Pneumonia.International journal of general medicine · 2025Article
- Inflammation scores based on C-reactive protein and albumin predict mortality in hospitalized older patients independent of the admission diagnosis.Immunity & ageing : I & A · 2024Article
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- Risk Factors of Postoperative Complication and Hospital Mortality after Colorectal Perforation Surgery.Journal of the anus, rectum and colon · 2024Article
- Impact of Dietary Fiber on Inflammation and Insulin Resistance in Older Patients: A Narrative Review.Nutrients · 2023Review
- Evaluation of Inflammation-Based Prognostic Risk Scores in Predicting in-Hospital Mortality Risk in COVID-19 Patients: A Cross-Sectional Retrospective Study.Infectious diseases & clinical microbiology · 2023Article
- Chronic activation of cardiac Atg-5 and pancreatic Atg-7 by intermittent fasting alleviates acute myocardial infarction in old rats.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2022Article
- Prediction of hospital mortality after colorectal perforation surgery from inflammation-based prognostic scores.Surgery open science · 2022Article
- Expression of ATP-binding cassette subfamily B member 1 gene in peripheral blood of patients with acute myocardial infarction.Bioengineered · 2022Article
- Predictors of short- and long-term mortality among acutely admitted older patients: role of inflammation and frailty.Aging clinical and experimental research · 2022Observational
- Systemic immune-inflammation index independently predicts poor survival of older adults with hip fracture: a prospective cohort study.BMC geriatrics · 2021Article
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6 authors.
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No grant is acknowledged in the PubMed record.
Abstract
objectiveEmerging evidence suggests that systemic inflammation is a predictor of poor prognosis in acute myocardial infarction (AMI). In this study, we sought to assess whether inflammation-based prognostic scores are associated with in-hospital outcomes in elderly patients with AMI.
methodsIn this retrospective study, patients who were over 75-years-old and met the diagnostic criteria for AMI were consecutively recruited from January 1, 2016, to March 31, 2019. Logistic regression and receiver-operating characteristic (ROC) analyses were performed to evaluate the predictive value of the inflammation-based Glasgow Prognostic Score (GPS), Prognostic Index (PI) and Prognostic Nutritional Index (PNI).
resultsA total of 273 patients were enrolled. The incidence of major cardiovascular adverse events (MACEs) and mortality during hospitalization increased significantly with increasing GPS and PI scores. Multiple logistic regression showed that the GPS was independently associated with MACEs (score 1, RR: 6.711, 95% CI: 1.409-31.968; score 2, RR: 14.063, 95% CI: 3.018-65.535) and mortality (score 1, RR: 8.656, 95% CI: 1.068-70.126; score 2, RR: 10.549, 95% CI: 1.317-84.465). The PI was also independently predictive of MACEs (score 2, RR: 5.132, 95% CI: 1.451-18.148). No significant difference was observed in the PNI between patients with different in-hospital outcomes. When in-hospital MACEs were used as an endpoint, the area under the curve (AUC) of the GPS was 0.740 (95% CI 0.678-0.802), and the AUC of the PI was 0.703 (95% CI 0.634-0.773). When mortality was used as an endpoint, the AUC of the GPS was 0.677 (95% CI 0.602-0.753), and the AUC of the PI was 0.667 (95% CI 0.577-0.757).
conclusionThe severity of systemic inflammation is a strong predictor of poor prognosis in elderly patients with AMI. Among these three inflammation-based prognostic scores, the GPS has a better predictive value than the PI and PNI for in-hospital MACEs and mortality.
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