ArticleScientific reports2019
Cell type specific transcriptional reprogramming of maize leaves during Ustilago maydis induced tumor formation.
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 23 citations in OpenAlex.
- Induction Medium to Analyze In Vitro Morphological Changes and Biotrophic Features in Sporidia of Ustilago maydis.Methods in molecular biology (Clifton, N.J.) · 2026Article
- Pathogenesis, Host Resistance and Integrated Management of Sugarcane Smut Caused by Sporisorium scitamineum: A Comprehensive Review.Molecular plant pathology · 2025Review
- Heat stress at the bicellular stage inhibits sperm cell development and transport into pollen tubes.Plant physiology · 2024Article
- A transcriptional activator effector of Ustilago maydis regulates hyperplasia in maize during pathogen-induced tumor formation.Nature communications · 2023Article
- Genome-Wide Characterization of the Maize (International journal of molecular sciences · 2023Article
- Combination of in vivo proximity labeling and co-immunoprecipitation identifies the host target network of a tumor-inducing effector in the fungal maize pathogen Ustilago maydis.Journal of experimental botany · 2023Article
- Special issue: Genetics of maize-microbe interactions.Molecular plant pathology · 2023Article
- Early infection response of fungal biotrophFrontiers in plant science · 2022Article
- Article
- Physiological Basis of Smut Infectivity in the Early Stages of Sugar Cane Colonization.Journal of fungi (Basel, Switzerland) · 2021Review
- UnderstandingJournal of fungi (Basel, Switzerland) · 2020Review
- Roles of plant retinoblastoma protein: cell cycle and beyond.The EMBO journal · 2020Review
- Beyond What Your Retina Can See: Similarities of Retinoblastoma Function between Plants and Animals, from Developmental Processes to Epigenetic Regulation.International journal of molecular sciences · 2020Review
- The two paralogous kiwellin proteins KWL1 and KWL1-b from maize are structurally related and have overlapping functions in plant defense.The Journal of biological chemistry · 2020Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Ustilago maydis is a biotrophic pathogen and well-established genetic model to understand the molecular basis of biotrophic interactions. U. maydis suppresses plant defense and induces tumors on all aerial parts of its host plant maize. In a previous study we found that U. maydis induced leaf tumor formation builds on two major processes: the induction of hypertrophy in the mesophyll and the induction of cell division (hyperplasia) in the bundle sheath. In this study we analyzed the cell-type specific transcriptome of maize leaves 4 days post infection. This analysis allowed identification of key features underlying the hypertrophic and hyperplasic cell identities derived from mesophyll and bundle sheath cells, respectively. We examined the differentially expressed (DE) genes with particular focus on maize cell cycle genes and found that three A-type cyclins, one B-, D- and T-type are upregulated in the hyperplasic tumorous cells, in which the U. maydis effector protein See1 promotes cell division. Additionally, most of the proteins involved in the formation of the pre-replication complex (pre-RC, that assure that each daughter cell receives identic DNA copies), the transcription factors E2F and DPa as well as several D-type cyclins are deregulated in the hypertrophic cells.
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