Evidence map›Paper›PMID 31308253›Full record

ArticleMolecular & cellular proteomics : MCP2019

Glycan Markers of Human Stem Cells Assigned with Beam Search Arrays.

Nian Wu, Lisete M Silva, Yan Liu, Yibing Zhang, Chao Gao, Fuming Zhang, Li Fu, Yanfei Peng, Robert Linhardt, Toshisuke Kawasaki and 3 more

Open access · hybridAbstract read
In one paragraph

Article in Molecular & cellular proteomics : MCP, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 28 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Serum antibody screening using glycan arrays.Chemical Society reviews · 2024
    Review
  7. Article
  8. Paradoxical Expression of R-10G-reactive Antigen in Human Testicular Embryonal Carcinoma.The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society · 2023
    Article
  9. Review
  10. Article
  11. Beta3Gn-T7 Is a Keratan Sulfate β1,3Frontiers in neuroanatomy · 2022
    Article
  12. Apical Membrane Expression of Distinct Sulfated Glycans Is a Characteristic Feature of Ductules and Their Reactive and Neoplastic Counterparts.The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society · 2021
    Article
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 3 countries.

Nian WuGlycosciences Laboratory, Department of Medicine, Imperial College London, London W12 0NN, United Kingdom.
Lisete M SilvaGlycosciences Laboratory, Department of Medicine, Imperial College London, London W12 0NN, United Kingdom.
Yan LiuGlycosciences Laboratory, Department of Medicine, Imperial College London, London W12 0NN, United Kingdom.
Yibing ZhangGlycosciences Laboratory, Department of Medicine, Imperial College London, London W12 0NN, United Kingdom.
Chao GaoGlycosciences Laboratory, Department of Medicine, Imperial College London, London W12 0NN, United Kingdom; Department of Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02215.
Fuming ZhangDepartment of Chemical and Biological Engineering, Center for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnic Institute, Troy, New York 12180.
Li FuDepartment of Chemical and Biological Engineering, Center for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnic Institute, Troy, New York 12180.
Yanfei PengDepartment of Chemical and Biological Engineering, Center for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnic Institute, Troy, New York 12180.
Robert LinhardtDepartment of Chemical and Biological Engineering, Center for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnic Institute, Troy, New York 12180.
Toshisuke KawasakiResearch Center for Glycobiotechnology, Ritsumeikan University, Noji-Higashi, 1-1-1, Kusatsu Shiga 525-8577, Japan.
Barbara MulloyGlycosciences Laboratory, Department of Medicine, Imperial College London, London W12 0NN, United Kingdom.
Wengang ChaiGlycosciences Laboratory, Department of Medicine, Imperial College London, London W12 0NN, United Kingdom. Electronic address: w.chai@imperial.ac.uk.
Ten FeiziGlycosciences Laboratory, Department of Medicine, Imperial College London, London W12 0NN, United Kingdom. Electronic address: t.feizi@imperial.ac.uk.
Clovis Oncology (United Kingdom) · GBRensselaer Polytechnic Institute · USBeth Israel Deaconess Medical Center · USRitsumeikan University · JP

Funding

Endothelial glycocalyx reconstitution during sepsisR01HL125371 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI LINHARDT, ROBERT J, SCHMIDT, ERIC PETER · 2014 to 2018
$3.4M
An Automated Platform for the CE-MS Analysis of GlycosaminoglycansU01CA231074 · NCI · UNIVERSITY OF GEORGIA · PI AMSTER, I JONATHAN · 2018 to 2020
$895k
Medical Research Council MC_U117533887NCI NIH HHS U01 CA231074NHLBI NIH HHS R01 HL125371Wellcome Trust 108430/Z/15/ZWellcome Trust FC001029
6 · The paper itself

Abstract

Glycan antigens recognized by monoclonal antibodies have served as stem cell markers. To understand regulation of their biosynthesis and their roles in stem cell behavior precise assignments are required. We have applied state-of-the-art glycan array technologies to compare the glycans bound by five antibodies that recognize carbohydrates on human stem cells. These are: FC10.2, TRA-1-60, TRA-1-81, anti-i and R-10G. Microarray analyses with a panel of sequence-defined glycans corroborate that FC10.2, TRA-1-60, TRA-1-81 recognize the type 1-(Galβ-3GlcNAc)-terminating backbone sequence,

Indexed as

Antibodies, MonoclonalAntigens, SurfaceBiomarkersCarbohydrate SequenceCells, CulturedEmbryonic Stem CellsHumansMass SpectrometryPolysaccharidesProtein Array AnalysisProteoglycansAntibodies, MonoclonalAntigens, SurfaceBiomarkersPolysaccharidesProteoglycansTRA-1-60 antigen, humanTRA-1-81 antigen, humanantibodiesglycan arraysglycan markersglycan rolesglycomicsgrowth factorskeratan sulfatemass spectrometrymicro arraysNMRStem cells

Identifiers

PMID31308253
PMCPMC6773554
OpenAlexW2957810229

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.