Evidence map›Paper›PMID 31308252›Full record

Trial reportMolecular & cellular proteomics : MCP2019

Small-protein Enrichment Assay Enables the Rapid, Unbiased Analysis of Over 100 Low Abundance Factors from Human Plasma.

Dylan J Harney, Amy T Hutchison, Zhiduan Su, Luke Hatchwell, Leonie K Heilbronn, Samantha Hocking, David E James, Mark Larance

Open access · hybridAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Molecular & cellular proteomics : MCP, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
4.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 56 citations in OpenAlex.

  1. Article
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  7. Article
  8. Review
  9. NovelJournal of fungi (Basel, Switzerland) · 2023
    Article
  10. Article
  11. Where are all the egg genes?Frontiers in cell and developmental biology · 2023
    Review
  12. Article
  13. Article
  14. Review
  15. A systematic analysis ofFrontiers in genetics · 2022
    Article
  16. Review
  17. AP-64, Encoded byBiomolecules · 2021
    Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Dylan J Harney‡Charles Perkins Centre, School of Life and Environmental Sciences, University of Sydney, Sydney, Australia.
Amy T Hutchison¶Discipline of Medicine, University of Adelaide, Adelaide, Australia.
Zhiduan Su‡Charles Perkins Centre, School of Life and Environmental Sciences, University of Sydney, Sydney, Australia.
Luke Hatchwell‡Charles Perkins Centre, School of Life and Environmental Sciences, University of Sydney, Sydney, Australia.
Leonie K Heilbronn¶Discipline of Medicine, University of Adelaide, Adelaide, Australia.
Samantha Hocking§Central Clinical School, Faculty of Medicine and Health, University of Sydney, Sydney, Australia.
David E James‡Charles Perkins Centre, School of Life and Environmental Sciences, University of Sydney, Sydney, Australia.
Mark Larance‡Charles Perkins Centre, School of Life and Environmental Sciences, University of Sydney, Sydney, Australia. Electronic address: mark.larance@sydney.edu.au.
The University of Sydney · AUThe University of Adelaide · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Unbiased and sensitive quantification of low abundance small proteins in human plasma (

Indexed as

Blood ProteinsCaloric RestrictionChromatography, LiquidEnzyme-Linked Immunosorbent AssayFastingFemaleHepcidinsHumansInsulinIntercellular Signaling Peptides and ProteinsIsotope LabelingProteomicsReproducibility of ResultsTandem Mass SpectrometryWeight LossWorkflowBlood ProteinsC5ORF46 protein, humanHepcidinsInsulinIntercellular Signaling Peptides and ProteinschemokineChromatographyhepcidinHormones*insulinInsulin resistanceintermittent fastingPlasma or serum analysisSerum/Plasma*

Identifiers

PMID31308252
PMCPMC6731089
OpenAlexW2960181340

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.