Evidence map›Paper›PMID 31308178›Full record

ArticleThe Journal of biological chemistry2019

Kevin Brown Chandler, Deborah R Leon, Jenevieve Kuang, Rosana D Meyer, Nader Rahimi, Catherine E Costello

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

56 citing papers in PubMed, 74 citations in OpenAlex.

  1. Encoding Cell-Surface Receptor Function Through Glycosylation: Lessons From CD44.Chembiochem : a European journal of chemical biology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Kevin Brown ChandlerCenter for Biomedical Mass Spectrometry, Department of Biochemistry, Boston University School of Medicine, Boston, Massachusetts 02118.
Deborah R LeonCenter for Biomedical Mass Spectrometry, Department of Biochemistry, Boston University School of Medicine, Boston, Massachusetts 02118.
Jenevieve KuangCenter for Biomedical Mass Spectrometry, Department of Biochemistry, Boston University School of Medicine, Boston, Massachusetts 02118; Department of Chemistry, Boston University, Boston, Massachusetts 02118.
Rosana D MeyerDepartment of Pathology and Laboratory Medicine, Boston University School of Medicine, Boston Massachusetts 02118.
Nader RahimiDepartment of Pathology and Laboratory Medicine, Boston University School of Medicine, Boston Massachusetts 02118.
Catherine E CostelloCenter for Biomedical Mass Spectrometry, Department of Biochemistry, Boston University School of Medicine, Boston, Massachusetts 02118; Department of Chemistry, Boston University, Boston, Massachusetts 02118. Electronic address: cecmsms@bu.edu.
Boston University · US

Funding

Mass Spectrometry Resource for Biology and MedicineP41GM104603 · NIGMS · BOSTON UNIVERSITY MEDICAL CAMPUS · PI COSTELLO, CATHERINE E. · 2012 to 2017
$10.4M
Legacy Support During Closure of the Mass Spectrometry Resource for Biology and MedicineR24GM134210 · NIGMS · BOSTON UNIVERSITY MEDICAL CAMPUS · PI COSTELLO, CATHERINE E. · 2019 to 2021
$2.1M
A Thermo-Fisher Scientific Orbitrap Fusion Lumos Tribrid Mass Spectrometer SystemS10OD021728 · OD · BOSTON UNIVERSITY MEDICAL CAMPUS · PI COSTELLO, CATHERINE E. · 2018 to 2018
$1.4M
MALDI-TOF/TOF MS TO SUPPORT BIOMEDICAL RESEARCHS10OD010724 · OD · BOSTON UNIVERSITY MEDICAL CAMPUS · PI COSTELLO, CATHERINE E. · 2012 to 2012
$590k
IGPR-1 in colon cancer chemotherapyR21CA193958 · NCI · BOSTON UNIVERSITY MEDICAL CAMPUS · PI RAHIMI, NADER · 2015 to 2016
$392k
Overcoming the resistance to anti-angiogenesis therapyR21CA191970 · NCI · BOSTON UNIVERSITY MEDICAL CAMPUS · PI RAHIMI, NADER · 2015 to 2016
$392k
Impaired Glycosylation of Vascular Endothelial Growth Factor Receptor 2 in Tumor AngiogenesisF32CA196157 · NCI · BOSTON UNIVERSITY MEDICAL CAMPUS · PI CHANDLER, KEVIN BROWN · 2015 to 2017
$168k
NCI NIH HHS F32 CA196157NCI NIH HHS R21 CA191970NCI NIH HHS R21 CA193958NIGMS NIH HHS P41 GM104603NIGMS NIH HHS R24 GM134210NIH HHS S10 OD010724NIH HHS S10 OD021728
6 · The paper itself

Abstract

The tumor microenvironment and proinflammatory signals significantly alter glycosylation of cell-surface proteins on endothelial cells. By altering the

Indexed as

Cell LineGlycosylationHumansHuman Umbilical Vein Endothelial CellsLigandsPolysaccharidesSignal TransductionVascular Endothelial Growth Factor Receptor-2KDR protein, humanLigandsPolysaccharidesVascular Endothelial Growth Factor Receptor-2angiogenesisangiogenic signalingcytokine signalingendothelial cellendothelial signalingglycosylationN-glycanN-linked glycosylationreceptor tyrosine kinasesialic acidvascular endothelial growth factor receptor 2 (VEGFR2)vascular endothelial growth factor (VEGF)

Identifiers

PMID31308178
PMCPMC6721943
OpenAlexW2958658855

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.