Evidence map›Paper›PMID 31308093›Full record

ArticleJournal of immunology (Baltimore, Md. : 1950)2019

Primary EBV Infection Induces an Acute Wave of Activated Antigen-Specific Cytotoxic CD4

Benjamin J Meckiff, Kristin Ladell, James E McLaren, Gordon B Ryan, Alison M Leese, Eddie A James, David A Price, Heather M Long

Abstract read
In one paragraph

Article in Journal of immunology (Baltimore, Md. : 1950), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed.

  1. Trial
  2. A tonsil organoid model reveals Epstein-Barr virus-infected germinal center B cell states during primary infection.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  3. Article
  4. Article
  5. Case Report: NovelFrontiers in immunology · 2026
    Article
  6. Review
  7. LANA-specific CD4Nature communications · 2025
    Article
  8. Cytotoxic T Cells: Kill, Memorize, and Mask to Maintain Immune Homeostasis.International journal of molecular sciences · 2025
    Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Benjamin J MeckiffInstitute of Immunology and Immunotherapy, University of Birmingham, Edgbaston, Birmingham B15 2TT, United Kingdom.
Kristin LadellDivision of Infection and Immunity, Cardiff University School of Medicine, Cardiff CF14 4XN, United Kingdom; and.ORCID 0000-0002-9856-2938
James E McLarenDivision of Infection and Immunity, Cardiff University School of Medicine, Cardiff CF14 4XN, United Kingdom; and.ORCID 0000-0002-7021-5934
Gordon B RyanInstitute of Immunology and Immunotherapy, University of Birmingham, Edgbaston, Birmingham B15 2TT, United Kingdom.
Alison M LeeseInstitute of Immunology and Immunotherapy, University of Birmingham, Edgbaston, Birmingham B15 2TT, United Kingdom.
Eddie A JamesTetramer Core Laboratory, Diabetes Program, Benaroya Research Institute at Virginia Mason, Seattle, WA 98101.ORCID 0000-0002-7217-5729
David A PriceDivision of Infection and Immunity, Cardiff University School of Medicine, Cardiff CF14 4XN, United Kingdom; and.ORCID 0000-0001-9416-2737
Heather M LongInstitute of Immunology and Immunotherapy, University of Birmingham, Edgbaston, Birmingham B15 2TT, United Kingdom; h.m.long@bham.ac.uk.ORCID 0000-0003-2139-8292

Funding

Wellcome TrustWellcome Trust 100326Z/12/Z
6 · The paper itself

Abstract

CD4

Indexed as

B-LymphocytesCD4 AntigensCD4-Positive T-LymphocytesCytotoxicity, ImmunologicEpstein-Barr Virus InfectionsHerpesvirus 4, HumanHumansImmunologic MemoryInfectious MononucleosisT-Lymphocytes, CytotoxicCD4 Antigens

Identifiers

PMID31308093
PMCPMC6697742

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.