Evidence map›Paper›PMID 31308055›Full record

ArticleLife science alliance2019

PRDM9 forms a trimer by interactions within the zinc finger array.

Theresa Schwarz, Yasmin Striedner, Andreas Horner, Karin Haase, Jasmin Kemptner, Nicole Zeppezauer, Philipp Hermann, Irene Tiemann-Boege

Open access · goldAbstract read
In one paragraph

Article in Life science alliance, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Theresa SchwarzInstitute of Biophysics, Johannes Kepler University, Linz, Austria.ORCID 0000-0002-6917-1364
Yasmin StriednerInstitute of Biophysics, Johannes Kepler University, Linz, Austria.
Andreas HornerInstitute of Biophysics, Johannes Kepler University, Linz, Austria.
Karin HaaseInstitute of Biophysics, Johannes Kepler University, Linz, Austria.
Jasmin KemptnerRed Cross Blood Transfusion Center Upper Austria, MedCampus II, Johannes Kepler University, Linz, Austria.
Nicole ZeppezauerInstitute of Biophysics, Johannes Kepler University, Linz, Austria.
Philipp HermannInstitute of Applied Statistics, Johannes Kepler University, Linz, Austria.ORCID 0000-0003-4556-6297
Irene Tiemann-BoegeInstitute of Biophysics, Johannes Kepler University, Linz, Austria irene.tiemann@jku.at.ORCID 0000-0002-3621-7020
Johannes Kepler University of Linz · ATAustrian Red Cross · AT

Funding

Austrian Science Fund FWF P 27698
6 · The paper itself

Abstract

PRDM9 is a trans-acting factor directing meiotic recombination to specific DNA-binding sites by its zinc finger (ZnF) array. It was suggested that PRDM9 is a multimer; however, we do not know the stoichiometry or the components inducing PRDM9 multimerization. In this work, we used

Indexed as

AnimalsBinding SitesDNAElectrophoretic Mobility Shift AssayHistone-Lysine N-MethyltransferaseHomologous RecombinationMass SpectrometryMeiosisMiceModels, MolecularProtein MultimerizationSolubilityZinc FingersDNAHistone-Lysine N-Methyltransferaseprdm9 protein, mouse

Identifiers

PMID31308055
PMCPMC6643046
OpenAlexW2956824755

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.