Evidence map›Paper›PMID 31307550›Full record

ArticleJournal of biomedical semantics2019

Phenotype annotation with the ontology of microbial phenotypes (OMP).

Deborah A Siegele, Sandra A LaBonte, Peter I-Fan Wu, Marcus C Chibucos, Suvarna Nandendla, Michelle G Giglio, James C Hu

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Article in Journal of biomedical semantics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

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0cells of the map it votes in
7citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Deborah A SiegeleDepartment of Biology, Texas A&M University, College Station, TX, USA.
Sandra A LaBonteDepartment of Biochemistry and Biophysics, Texas A&M University and Texas AgriLife Research, College Station, TX, USA.
Peter I-Fan WuDepartment of Biochemistry and Biophysics, Texas A&M University and Texas AgriLife Research, College Station, TX, USA.
Marcus C ChibucosInstitute for Genome Sciences, University of Maryland School of Medicine, Baltimore, MD, USA.
Suvarna NandendlaInstitute for Genome Sciences, University of Maryland School of Medicine, Baltimore, MD, USA.
Michelle G GiglioInstitute for Genome Sciences, University of Maryland School of Medicine, Baltimore, MD, USA.
James C HuDepartment of Biochemistry and Biophysics, Texas A&M University and Texas AgriLife Research, College Station, TX, USA. jimhu@tamu.edu.ORCID 0000-0001-9016-2684

Funding

The Disease Ontology Project: mechanistic profiles of human disease for biomedical and clinical researchU41HG008735 · NHGRI · UNIVERSITY OF MARYLAND BALTIMORE · PI SCHRIML, LYNN MARIE · 2017 to 2021
$3.4M
An Ontology for Microbial PhenotypesR01GM089636 · NIGMS · TEXAS A&M UNIVERSITY · PI HU, JAMES C · 2010 to 2016
$1.6M
NHGRI NIH HHS U41 HG008735NIGMS NIH HHS R01 GM089636
6 · The paper itself

Abstract

backgroundMicrobial genetics has formed a foundation for understanding many aspects of biology. Systematic annotation that supports computational data mining should reveal further insights for microbes, microbiomes, and conserved functions beyond microbes. The Ontology of Microbial Phenotypes (OMP) was created to support such annotation.

resultsWe define standards for an OMP-based annotation framework that supports the capture of a variety of phenotypes and provides flexibility for different levels of detail based on a combination of pre- and post-composition using OMP and other Open Biomedical Ontology (OBO) projects. A system for entering and viewing OMP annotations has been added to our online, public, web-based data portal.

conclusionsThe annotation framework described here is ready to support projects to capture phenotypes from the experimental literature for a variety of microbes. Defining the OMP annotation standard should support the development of new software tools for data mining and analysis in comparative phenomics.

Indexed as

Biological OntologiesMicrobiologyPhenotypeData CurationMetadataAnnotationBiomedical ontologiesCurationMicrobial geneticsMicrobial phenotypesMicrobiologyOntologyPhenotypes

Identifiers

PMID31307550
PMCPMC6631659

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.