ArticleBMC research notes2019
The clinico-pathological profile of non-Hodgkin's lymphoma in Aseer region of Saudi Arabia.
Article in BMC research notes, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 14 citations in OpenAlex.
- Article
- Article
- A Comprehensive Two-Decade Analysis of Lymphoma Incidence Patterns in Saudi Arabia.Journal of clinical medicine · 2024Article
- Clinical and Therapeutic Profile of Non-Hodgkin's Lymphoma: A Retrospective Study From a Najran Oncology Center.Cureus · 2023Article
- Immunophenotypic characterisation of non-Hodgkin lymphomas at a tertiary hospital in Ghana.Ecancermedicalscience · 2022Article
- Clinicopathological spectrum of Diffuse Large B Cell lymphoma: a study targeting population yet unexplored in Pakistan.BMC research notes · 2021Article
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Authors and funding
5 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveNon-Hodgkin lymphomas (NHL) are a group of neoplastic lymphoproliferative disorders, in which, its clinical spectrum, primary extra nodal variety, histopathology and Immunohistochemistry, remain lacking in Saudi Arabia. We aimed to assess the clinicopathologic patterns of NHL and the utility and diagnostic role of IHC immunophenotyping.
resultsPatients > 60 years of age had the highest incidence of NHL; male: female ratio was 1.27:1. The incidence of NHL has shown a steady increase in the Aseer region from 2011 to 2014. Twenty-Five percent of our patients presented with advanced disease (Stage IV). A total of 52% of patients presented with constitutional symptoms, while 43% showed generalized lymphadenopathy. Nearly half of our patients (49%) had primary NHL of extra nodal variety, where the stomach was the most commonly involved organ (13 cases). Diffuse large B cell lymphoma was the most common subtype of NHL in our population (59%). Most patients (82%) were positive for CD20 surface marker, while 60% were positive for CD45.
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