Evidence map›Paper›PMID 31307478›Full record

ArticleEnvironmental health : a global access science source2019

Susceptibility of prediabetes to the health effect of air pollution: a community-based panel study with a nested case-control design.

Yiqun Han, Yanwen Wang, Weiju Li, Xi Chen, Tao Xue, Wu Chen, Yunfei Fan, Xinghua Qiu, Tong Zhu

Open access · goldAbstract read
In one paragraph

Article in Environmental health : a global access science source, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
2.5field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 34 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Yiqun HanBIC-ESAT and SKL-ESPC, College of Environmental Sciences and Engineering and Centre for Environment and Health, Peking University, Beijing, 100871, China.
Yanwen WangBIC-ESAT and SKL-ESPC, College of Environmental Sciences and Engineering and Centre for Environment and Health, Peking University, Beijing, 100871, China.
Weiju LiPeking University Hospital, Peking University, Beijing, 100871, China.
Xi ChenBIC-ESAT and SKL-ESPC, College of Environmental Sciences and Engineering and Centre for Environment and Health, Peking University, Beijing, 100871, China.
Tao XueBIC-ESAT and SKL-ESPC, College of Environmental Sciences and Engineering and Centre for Environment and Health, Peking University, Beijing, 100871, China.
Wu ChenBIC-ESAT and SKL-ESPC, College of Environmental Sciences and Engineering and Centre for Environment and Health, Peking University, Beijing, 100871, China.
Yunfei FanBIC-ESAT and SKL-ESPC, College of Environmental Sciences and Engineering and Centre for Environment and Health, Peking University, Beijing, 100871, China.
Xinghua QiuBIC-ESAT and SKL-ESPC, College of Environmental Sciences and Engineering and Centre for Environment and Health, Peking University, Beijing, 100871, China.
Tong ZhuBIC-ESAT and SKL-ESPC, College of Environmental Sciences and Engineering and Centre for Environment and Health, Peking University, Beijing, 100871, China. tzhu@pku.edu.cn.
Peking University · CN

Funding

National Natural Science Foundation of China 41421064, 21190051, 41121004
6 · The paper itself

Abstract

backgroundRecent studies suggest that people with diabetes or who are at risk of developing diabetes, i.e. prediabetic (preDM), are potentially susceptible to air pollution, but the underlying mechanisms remain unclear because the existing epidemiological studies did not include healthy control groups and only focused on limited health outcomes. We hypothesized that acute exposure to ambient fine particles (PM

methodsWe recruited 60 preDM and 60 healthy individuals from a community of 22,343 adults in Beijing China, and arranged each subject to complete up to seven repeated clinical visits with measures of 6 cardiopulmonary biomarkers, 6 cytokines, 4 blood pressure and endothelial function outcomes and 4 glucose metabolism biomarkers.. Moving averaged daily ambient PM

resultsAll the subjects exhibited significant acute elevation of exhaled nitric oxide, white blood cells, neutrophils, interleukin-1α, and glycated haemoglobin with increased exposure to PM

conclusionsPreDM individuals are more susceptible to the acute cardiometabolic effect of air pollution than the healthy individuals. A considerable public health burden can be inferred, given the high prevalence of prediabetes and the ubiquity of air pollution in China and worldwide.

Indexed as

Air PollutantsAir PollutionBeijingCase-Control StudiesDisease SusceptibilityEnvironmental ExposureFemaleHumansMaleMiddle AgedParticle SizeParticulate MatterPrediabetic StateRisk FactorsAir PollutantsParticulate MatterCardiometabolic biomarkersPanel studyPM2.5PrediabetesSusceptibility

Identifiers

PMID31307478
PMCPMC6631920
OpenAlexW2961714738

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.