Evidence map›Paper›PMID 31307430›Full record

ArticleBMC nephrology2019

Association of functional and structural social support with chronic kidney disease among African Americans: the Jackson Heart Study.

Rasheeda K Hall, Clemontina A Davenport, Mario Sims, Cathleen Colón-Emeric, Tiffany Washington, Jennifer St Clair Russell, Jane Pendergast, Nrupen Bhavsar, Julia Scialla, Crystal C Tyson and 5 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC nephrology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 1 country.

Rasheeda K HallDuke University, Durham, NC, USA. rasheeda.stephens@duke.edu.ORCID 0000-0002-3057-4828
Clemontina A DavenportDuke University, Durham, NC, USA.
Mario SimsUniversity of Mississippi Medical Center, Jackson, MS, USA.
Cathleen Colón-EmericDuke University, Durham, NC, USA.
Tiffany WashingtonUniversity of Georgia, Athens, GA, USA.
Jennifer St Clair RussellDuke University, Durham, NC, USA.
Jane PendergastDuke University, Durham, NC, USA.
Nrupen BhavsarDuke University, Durham, NC, USA.
Julia SciallaDuke University, Durham, NC, USA.
Crystal C TysonDuke University, Durham, NC, USA.
Wei WangUniversity of Mississippi Medical Center, Jackson, MS, USA.
Yuan-I MinUniversity of Mississippi Medical Center, Jackson, MS, USA.
Bessie YoungUniversity of Washington, Seattle, WA, USA.
L Ebony BoulwareDuke University, Durham, NC, USA.
Clarissa J DiamantidisDuke University, Durham, NC, USA.
Duke University · USJackson Memorial Hospital · USUniversity of Georgia · USUniversity of Washington · US

Funding

Duke CTSA (Composite)UL1TR001117 · NCATS · DUKE UNIVERSITY · PI BOULWARE, LEIGH E, LI, JENNIFER S · 2013 to 2017
$41.3M
Deprescribing for Older Dialysis PatientsK76AG059930 · NIA · DUKE UNIVERSITY · PI HALL, RASHEEDA K · 2018 to 2022
$1.2M
Addressing Bias from Missing Data in EHR Based Studies of CVDK01HL140146 · NHLBI · DUKE UNIVERSITY · PI BHAVSAR, NRUPEN · 2018 to 2022
$829k
NCI CLINICAL INVESTIGATOR AWARD PROGRAMK08CA001117 · NCI · YALE UNIVERSITY · PI KOLETSKY, ALAN J · 1986 to 1986
–
NCATS NIH HHS UL1 TR001117NCATS NIH HHS UL1TR001117NHLBI NIH HHS HHSN268201800011INHLBI NIH HHS HHSN268201800012CNHLBI NIH HHS HHSN268201800012INHLBI NIH HHS HHSN268201800013INHLBI NIH HHS HHSN268201800014INHLBI NIH HHS HHSN268201800015INHLBI NIH HHS HSN268201800010INHLBI NIH HHS K01 HL140146NIA NIH HHS K76 AG059930NIA NIH HHS K76AG059930-01NIMHD NIH HHS HHSN268201800013I
6 · The paper itself

Abstract

backgroundThere is limited evidence on the relationship between social support and renal outcomes in African Americans. We sought to determine the association of social support with prevalent chronic kidney disease (CKD) and kidney function decline in an African American cohort. We also examined whether age modifies the association between social support and kidney function decline.

methodsWe identified Jackson Heart Study (JHS) participants with baseline (Exam in 2000-2004) functional and structural social support data via the Interpersonal Support Evaluation List (ISEL) and social network size questions, respectively. With ISEL as our primary exposure variable, we performed multivariable regression models to evaluate the association between social support and prevalent CKD [estimated glomerular filtration rate (eGFR) < 60 ml/min/1.73 m2 or urine albumin-creatinine ratio (ACR) ≥30 mg/g], eGFR decline, and rapid renal function decline (RRFD) (> 30% decrease in eGFR over approximately 10 years). All models were adjusted for baseline sociodemographics, diabetes, hypertension, smoking status, and body mass index; models for eGFR decline and RRFD were additionally adjusted for eGFR and ACR. In models for eGFR decline, we assessed for interaction between age and social support. For secondary analyses, we replaced ISEL with its individual domains (appraisal, belonging, self-esteem, and tangible) and social network size in separate models as exposure variables.

resultsOf 5301 JHS participants, 4015 (76%) completed the ISEL at baseline. 843 (21%) had low functional social support (ISEL score < 32). Participants with low (vs. higher) functional social support were more likely to have lower income (47% vs. 28%), be current or former tobacco users (39% vs. 30%), have diabetes (25% vs. 21%) or CKD (14% vs. 12%). After multivariable adjustment, neither ISEL or social network size were independently associated with prevalent CKD, eGFR decline, or RRFD. Of the ISEL domains, only higher self-esteem was associated with lower odds of prevalent CKD [OR 0.94 (95% CI 0.89-0.99)]. The associations between social support measures and eGFR decline were not modified by age.

conclusionsIn this African-American cohort, social support was not associated with prevalent CKD or kidney function decline. Further inquiry of self-esteem's role in CKD self-management and renal outcomes is warranted.

Indexed as

Black or African AmericanSocial SupportAdultAgedCross-Sectional StudiesFemaleGlomerular Filtration RateHumansLongitudinal StudiesMaleMiddle AgedRenal Insufficiency, ChronicAgedChronic renal insufficiencyMinority healthSocial network

Identifiers

PMID31307430
PMCPMC6633656
OpenAlexW2958567683

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.