Evidence map›Paper›PMID 31307422›Full record

ArticleBMC public health2019

Antibiotic dispensation rates among participants in community-driven health research projects in Arctic Canada.

Kathleen Williams, Amy Colquhoun, Rachel Munday, Karen J Goodman, CANHelp Working Group

Open access · goldAbstract read
In one paragraph

Article in BMC public health, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Prevalence and correlates of oral antibiotic use in Canada.Canada communicable disease report = Releve des maladies transmissibles au Canada · 2024
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Kathleen WilliamsSchool of Public Health, University of Alberta, 7-142 Katz Building, 87 Ave - 114 St, Edmonton, AB, T6G 2E1, Canada. kfwillia@ualberta.ca.ORCID http://orcid.org/0000-0001-8787-607X
Amy ColquhounSchool of Public Health, University of Alberta, 7-142 Katz Building, 87 Ave - 114 St, Edmonton, AB, T6G 2E1, Canada.
Rachel MundaySusie Husky Health Centre, Aklavik, NT, Canada.
Karen J GoodmanSchool of Public Health, University of Alberta, 7-142 Katz Building, 87 Ave - 114 St, Edmonton, AB, T6G 2E1, Canada.
CANHelp Working Group
University of Alberta · CA

Funding

INDOOR AIR POLLUTION AND CHILD ARI: A RANDOMIZED TRIALR01ES010178 · NIEHS · UNIVERSITY OF CALIFORNIA BERKELEY · PI SMITH, KIRK R · 2001 to 2009
$4.5M
Alberta Innovates - Health Solutions 201201159ArcticNet RES0010178NIEHS NIH HHS R01 ES010178
6 · The paper itself

Abstract

backgroundCommunity-driven projects that aim to address public concerns about health risks from H. pylori infection in Indigenous Arctic communities (estimated H. pylori prevalence = 64%) show frequent failure of treatment to eliminate the bacterium. Among project participants, treatment effectiveness is reduced by antibiotic resistance of infecting H. pylori strains, which in turn, is associated with frequent exposure to antibiotics used to treat other infections. This analysis compares antibiotic dispensation rates in Canadian Arctic communities to rates in urban and rural populations in Alberta, a southern Canadian province.

methodsProject staff collected antibiotic exposure histories for 297 participants enrolled during 2007-2012 in Aklavik, Tuktoyaktuk, and Fort McPherson in the Northwest Territories, and Old Crow, Yukon. Medical chart reviews collected data on systemic antibiotic dispensations for the 5-year period before enrolment for each participant. Antibiotic dispensation data for urban Edmonton, Alberta (average population ~ 860,000) and rural northern Alberta (average population ~ 450,000) during 2010-2013 were obtained from the Alberta Government Interactive Health Data Application.

resultsAntibiotic dispensation rates, estimated as dispensations/person-years (95% confidence interval) were: in Arctic communities, 0.89 (0.84, 0.94); in Edmonton, 0.55 (0.55, 0.56); in rural northern Alberta, 0.63 (0.62, 0.63). Antibiotic dispensation rates were higher in women and older age groups in all regions. In all regions, the highest dispensation rates occurred for β-lactam and macrolide antibiotic classes.

conclusionsThese results show more frequent antibiotic dispensation in Arctic communities relative to an urban and rural southern Canadian population.

Indexed as

AdolescentAdultAgedAged, 80 and overAnti-Bacterial AgentsArctic RegionsCanadaChildChild, PreschoolFemaleHelicobacter InfectionsHelicobacter pyloriHumansMaleMiddle AgedResidence CharacteristicsAnti-Bacterial AgentsAntibiotic exposureAntibiotic resistanceArctic CanadaHelicobacter pyloriTreatment failure

Identifiers

PMID31307422
PMCPMC6631451
OpenAlexW2960671116

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.