Evidence map›Paper›PMID 31307320›Full record

ReviewJournal of pediatric oncology nursing : official journal of the Association of Pediatric Oncology Nurses

Symptom Biomarkers for Children Receiving Treatment for Cancer: State of the Science.

Belinda N Mandrell, Janice S Withycombe

Abstract readReview
In one paragraph

Review in Journal of pediatric oncology nursing : official journal of the Association of Pediatric Oncology Nurses. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Belinda N Mandrell1 St. Jude Children's Research Hospital, Memphis, TN, USA.ORCID 0000-0002-6041-7559
Janice S Withycombe2 Emory University, Atlanta, GA, USA.

Funding

NCTN BIQSFP ANBL1531 (NRT)U10CA180886 · NCI · PUBLIC HEALTH INSTITUTE · PI Douglas S. Hawkins · 2014 to 2026
$390.6M
Symptom Assessment during Childhood Cancer TreatmentR13CA232442 · NCI · DUKE UNIVERSITY · PI HOCKENBERRY, MARILYN J · 2018 to 2018
$5k
NCI NIH HHS R13 CA232442NCI NIH HHS U10 CA180886
6 · The paper itself

Abstract

The Children's Oncology Group Nursing Discipline has identified the most concerning symptoms during childhood cancer treatment and the need for continued symptom assessment and intervention during treatment trajectory. To develop appropriate interventions, symptom science strategies must explore the biological mechanisms associated with symptoms of cancer and cancer treatment. To explore the associated biological mechanisms, biomarkers have been recommended for inclusion in symptom science studies, when applicable. The biomarker assessed, as well as the method of collection and storage, can affect the reliability and validity of the study results and clinical implication. This review will describe biomarkers that have been described in pediatric oncology symptom science research and provides special considerations for specimen collection and processing.

Indexed as

AdolescentBiomarkersBiomedical ResearchChildChild, PreschoolCytokinesFemaleForecastingHumansHydrocortisoneInfantMaleMelatoninNeoplasmsOxidative StressReproducibility of ResultsBiomarkersCytokinesHydrocortisoneMelatoninbimarkerscortisolcytokinesoxidative stress

Identifiers

PMID31307320
PMCPMC7197220

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.