Evidence map›Paper›PMID 31307289›Full record

ArticleJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism2020

MRI evaluation of cerebrovascular reactivity in obstructive sleep apnea.

Pei-Hsin Wu, Ana E Rodríguez-Soto, Zachary B Rodgers, Erin K Englund, Andrew Wiemken, Michael C Langham, John A Detre, Richard J Schwab, Wensheng Guo, Felix W Wehrli

Open access · bronzeAbstract read
In one paragraph

Article in Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Recent Advances in MR Imaging-based Quantification of Brain Oxygen Metabolism.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2024
    Review
  7. Cerebrovascular Reactivity Following Spinal Cord Injury.Topics in spinal cord injury rehabilitation · 2024
    Article
  8. Article
  9. Article
  10. Patterns of ischemic posterior circulation strokes: A clinical, anatomical, and radiological review.International journal of stroke : official journal of the International Stroke Society · 2022
    Review
  11. MRI evaluation of cerebral metabolic rate of oxygen (CMROJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2022
    Article
  12. Article
  13. Altered regional cerebral blood flow in obstructive sleep apnea is associated with sleep fragmentation and oxygen desaturation.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2021
    Article
  14. Article
  15. Cerebral metabolic rate of oxygen during transition from wakefulness to sleep measured with high temporal resolution OxFlow MRI with concurrent EEG.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2021
    Article
  16. Acute e-cig inhalation impacts vascular health: a study in smoking naïve subjects.American journal of physiology. Heart and circulatory physiology · 2021
    Article
  17. Review
  18. Review
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Pei-Hsin WuDepartment of Radiology, University of Pennsylvania Health System, Philadelphia, PA, USA.
Ana E Rodríguez-SotoDepartment of Radiology, University of Pennsylvania Health System, Philadelphia, PA, USA.
Zachary B RodgersDepartment of Radiology, University of Pennsylvania Health System, Philadelphia, PA, USA.
Erin K EnglundDepartment of Radiology, University of Pennsylvania Health System, Philadelphia, PA, USA.ORCID 0000-0002-0231-1289
Andrew WiemkenDivision of Sleep Medicine, Department of Medicine, University of Pennsylvania Health System, Philadelphia, PA, USA.
Michael C LanghamDepartment of Radiology, University of Pennsylvania Health System, Philadelphia, PA, USA.
John A DetreDepartment of Neurology, University of Pennsylvania, Philadelphia, PA, USA.
Richard J SchwabDivision of Sleep Medicine, Department of Medicine, University of Pennsylvania Health System, Philadelphia, PA, USA.
Wensheng GuoDepartment of Biostatistics and Epidemiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, USA.
Felix W WehrliDepartment of Radiology, University of Pennsylvania Health System, Philadelphia, PA, USA.
University of Pennsylvania Health System · USUniversity of Pennsylvania · US

Funding

Phenotypic Diversity in COVID-19UL1TR001878 · NCATS · UNIVERSITY OF PENNSYLVANIA · PI FITZGERALD, GARRET A · 2016 to 2025
$102.4M
Training in Structural, Physiologic and Functional MRIT32EB020087 · NIBIB · UNIVERSITY OF PENNSYLVANIA · PI JAMES C GEE, Chamith Sudesh Rajapakse · 2016 to 2026
$2.1M
Neurometabolic Assessment of Obstructive Sleep Apnea by MRIR01HL122754 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI WEHRLI, FELIX W · 2015 to 2018
$1.7M
NCATS NIH HHS UL1 TR001878NHLBI NIH HHS R01 HL122754NIBIB NIH HHS T32 EB020087
6 · The paper itself

Abstract

Obstructive sleep apnea (OSA) is characterized by intermittent obstruction of the airways during sleep. Cerebrovascular reactivity (CVR) is an index of cerebral vessels' ability to respond to a vasoactive stimulus, such as increased CO

Indexed as

AdultAgedBrainBreath HoldingCerebrovascular CirculationFemaleHumansMagnetic Resonance ImagingMaleMiddle AgedSleep Apnea, ObstructiveBOLDbreath-hold indexcerebrovascular reactivityobstructive sleep apnearadial phase-contrast MRI

Identifiers

PMID31307289
PMCPMC7238371
OpenAlexW2959507273

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.