Evidence map›Paper›PMID 31307288›Full record

ArticleJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism2020

The functional role of hemojuvelin in acute ischemic stroke.

Guang-Huar Young, Sung-Chun Tang, Vin-Cent Wu, Kuo-Chuan Wang, Jing-Yi Nong, Po-Yuan Huang, Chaur-Jong Hu, Hung-Yi Chiou, Jiann-Shing Jeng, Chung Y Hsu

Open access · bronzeAbstract read
In one paragraph

Article in Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Functional Roles of Furin in Cardio-Cerebrovascular Diseases.ACS pharmacology & translational science · 2024
    Review
  4. Iron Deposition in Brain: Does Aging Matter?International journal of molecular sciences · 2022
    Review
  5. Article
  6. Article
  7. Towards blood biomarkers for stroke patients.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2021
    Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Guang-Huar YoungDivision of Scientific Research, Energenesis Biomedical, Taipei.
Sung-Chun TangStroke Center and Department of Neurology, National Taiwan University Hospital, Taipei.
Vin-Cent WuDepartment of Internal Medicine, National Taiwan University Hospital, Taipei.
Kuo-Chuan WangDepartment of Surgery, National Taiwan University Hospital, Taipei.
Jing-Yi NongDepartment of Internal Medicine, National Taiwan University Hospital, Taipei.
Po-Yuan HuangStroke Center and Department of Neurology, National Taiwan University Hospital, Taipei.
Chaur-Jong HuDepartment of Neurology, Taipei Medical University-Shuang Ho Hospital, Taipei.
Hung-Yi ChiouSchool of Public Health, Taipei Medical University, Taipei.
Jiann-Shing JengStroke Center and Department of Neurology, National Taiwan University Hospital, Taipei.
Chung Y HsuGraduate Institute of Clinical Medical Science, China Medical University, Taichung.
National Taiwan University Hospital · TWChina Medical University · TWTaipei Medical University · TWTaipei Medical University-Shuang Ho Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Our study aimed to establish the role of hemojuvelin (HJV) in acute ischemic stroke (AIS). We performed immunohistochemistry for HJV expression in human brain tissues from 10 AIS and 2 non-stroke autopsy subjects. Plasma HJV was measured in 112 AIS patients within 48 h after stroke. The results showed significantly increased HJV expression in brain tissues from AIS patients compare to non-stroke subjects. After adjusting for clinical variables, plasma levels of HJV within 48 h after stroke were an independent predictor of poor functional outcome three months post-stroke (OR:1.78, 95% CI: 1.03-3.07;

Indexed as

AgedAnimalsBiomarkersFemaleGPI-Linked ProteinsHemochromatosis ProteinHumansIschemic StrokeMaleMiceMice, Inbred C57BLMiddle AgedNeuronsRecovery of FunctionBiomarkersGPI-Linked ProteinsHemochromatosis ProteinHJV protein, humanHJV protein, mouseAcute ischemic strokehemojuvelin proteinironneuronoutcome

Identifiers

PMID31307288
PMCPMC7238368
OpenAlexW2956616119

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.