Evidence map›Paper›PMID 31307270›Full record

ArticleJournal of the American Heart Association2019

Effect of Intensive and Standard Clinic-Based Hypertension Management on the Concordance Between Clinic and Ambulatory Blood Pressure and Blood Pressure Variability in SPRINT.

Lama Ghazi, Nicholas M Pajewski, Dena E Rifkin, Jeffrey T Bates, Tara I Chang, William C Cushman, Stephen P Glasser, William E Haley, Karen C Johnson, William J Kostis and 8 more

Abstract read
In one paragraph

Article in Journal of the American Heart Association, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Trial
  4. Trial
  5. Trial
  6. Remote Blood Pressure Monitoring: A Comprehensive Review.American journal of hypertension · 2026
    Review
  7. Mean-ing Beyond Office Blood Pressure.Journal of the American Heart Association · 2023
    Article
  8. Review
  9. Persistence of blood pressure phenotypes defined by office and ambulatory measurements in youth of 5 to 15 years of age.Hypertension research : official journal of the Japanese Society of Hypertension · 2023
    Article
  10. Article
  11. Validating cuffless continuous blood pressure monitoring devices.Cardiovascular digital health journal · 2023
    Review
  12. Article
  13. Blood pressure variability assessed by office, home, and ambulatory measurements: comparison, agreement, and determinants.Hypertension research : official journal of the Japanese Society of Hypertension · 2021
    Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Lama Ghazi1 Division of Public Health Department of Epidemiology and Community Health University of Minnesota Minneapolis MN.
Nicholas M Pajewski2 Division of Public Health Sciences Department of Biostatistical Sciences Wake Forest School of Medicine Winston-Salem NC.
Dena E Rifkin3 Division of Nephrology Veterans Affairs Health System and University of California San Diego CA.
Jeffrey T Bates4 Michael E. DeBakey Veterans Affairs Medical Center and Baylor College of Medicine Houston TX.
Tara I Chang5 Division of Nephrology Stanford University School of Medicine Palo Alto CA.
William C Cushman6 Memphis Veterans Affairs Medical Center Memphis TN.
Stephen P Glasser7 Division of Cardiology Department of Internal Medicine University of Kentucky College of Medicine Lexington KY.
William E Haley8 Division of Nephrology and Hypertension Mayo Clinic Jacksonville FL.
Karen C Johnson9 Department of Preventive Medicine University of Tennessee Health Science Center Memphis TN.
William J Kostis10 Division of Cardiovascular Disease and Hypertension Rutgers Robert Wood Johnson Medical School New Brunswick NJ.
Vasilios Papademetriou11 Department of Veterans Affairs and Georgetown University Washington DC.
Mahboob Rahman12 Case Western Reserve University University Hospitals Cleveland Medical Center Louis Stokes Cleveland VA Medical Center Cleveland OH.
Debra L Simmons13 Department of Internal Medicine University of Utah Salt Lake City UT.
Addison Taylor4 Michael E. DeBakey Veterans Affairs Medical Center and Baylor College of Medicine Houston TX.
Paul K Whelton15 Tulane University School of Public Health and Tropical Medicine New Orleans LA.
Jackson T Wright16 Clinical Hypertension Program Division of Nephrology and Hypertension University Hospitals Cleveland Medical Center Cleveland OH.
Udayan Y Bhatt17 Division of Nephrology The Ohio State University, Wexner Medical Center Columbus OH.
Paul E Drawz18 Division of Renal Diseases and Hypertension University of Minnesota Minneapolis MN.

Funding

INSTITUTIONAL CLINICAL AND TRANSLATIONAL SCIENCE AWARDUL1RR024134 · NCRR · UNIVERSITY OF PENNSYLVANIA · PI FITZGERALD, GARRET A · 2006 to 2011
$70.4M
Clinical and Translational Science Collaborative of ClevelandUL1TR000439 · NCATS · CASE WESTERN RESERVE UNIVERSITY · PI KONSTAN, MICHAEL W. · 2012 to 2016
$50.0M
Michigan Institute for Clinical and Health Research (MCHR)UL1TR000433 · NCATS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MASHOUR, GEORGE ALEXANDER · 2012 to 2016
$49.9M
Stanford Center for Clinical & Translational Education and Research (Spectrum)UL1TR003142 · NCATS · STANFORD UNIVERSITY · PI O'HARA, RUTH M · 2019 to 2023
$45.0M
The Vanderbilt Institute for Clinical and Translational Research (VICTR)UL1TR000445 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI BERNARD, GORDON RAPHAEL · 2012 to 2016
$41.4M
Institutional Clinical and Translational Science AwardUL1TR000003 · NCATS · UNIVERSITY OF PENNSYLVANIA · PI FITZGERALD, GARRET A · 2012 to 2015
$38.9M
Clinical and Translational Science Collaborative of ClevelandUL1TR002548 · NCATS · CASE WESTERN RESERVE UNIVERSITY · PI MCCOMSEY, GRACE A · 2018 to 2022
$35.5M
University of Minnesota Clinical and Translational Science Institute (UMN CTSI)UL1TR002494 · NCATS · UNIVERSITY OF MINNESOTA · PI BLAZAR, BRUCE R, WEISDORF, DANIEL J · 2018 to 2022
$34.9M
Tufts Clinical and Translational Research InstituteUL1TR001064 · NCATS · TUFTS UNIVERSITY BOSTON · PI SELKER, HARRY P. · 2013 to 2017
$26.4M
University of Iowa Clinical and Translational Science Program (TL1)UL1RR025755 · NCRR · OHIO STATE UNIVERSITY · PI JACKSON, REBECCA D · 2008 to 2011
$26.3M
CTSA INFRASTRUCTURE FOR PEDIATRIC RESEARCHUL1RR025771 · NCRR · BOSTON UNIVERSITY MEDICAL CAMPUS · PI CENTER, DAVID M. · 2008 to 2011
$17.6M
TUFTS CLINICAL AND TRANSLATION SCIENCE INSTITUTE (UL1): BPCAUL1RR025752 · NCRR · TUFTS UNIVERSITY BOSTON · PI SELKER, HARRY P. · 2008 to 2011
$17.6M
Intramural NIH HHS ZIA TR000017NCATS NIH HHS UL1 TR000002NCATS NIH HHS UL1 TR000003NCATS NIH HHS UL1 TR000050NCATS NIH HHS UL1 TR000064NCATS NIH HHS UL1 TR000073NCATS NIH HHS UL1 TR000075NCATS NIH HHS UL1 TR000093NCATS NIH HHS UL1 TR000105NCATS NIH HHS UL1 TR000433NCATS NIH HHS UL1 TR000439NCATS NIH HHS UL1 TR000445NCATS NIH HHS UL1 TR001064NCATS NIH HHS UL1 TR002494NCATS NIH HHS UL1 TR002548NCATS NIH HHS UL1 TR003142NCRR NIH HHS UL1 RR024134NCRR NIH HHS UL1 RR025752NCRR NIH HHS UL1 RR025755NCRR NIH HHS UL1 RR025771NICHD NIH HHS K12 HD043451NIDDK NIH HHS K23 DK091521NIDDK NIH HHS R03 DK100530NIDDK NIH HHS R03 DK105314NIGMS NIH HHS P30 GM103337
6 · The paper itself

Abstract

Background Blood pressure ( BP ) varies over time within individual patients and across different BP measurement techniques. The effect of different BP targets on concordance between BP measurements is unknown. The goals of this analysis are to evaluate concordance between (1) clinic and ambulatory BP , (2) clinic visit-to-visit variability and ambulatory BP variability, and (3) first and second ambulatory BP and to evaluate whether different clinic targets affect these relationships. Methods and Results The SPRINT (Systolic Blood Pressure Intervention Trial) ambulatory BP monitoring ancillary study obtained ambulatory BP readings in 897 participants at the 27-month follow-up visit and obtained a second reading in 203 participants 293±84 days afterward. There was considerable lack of agreement between clinic and daytime ambulatory systolic BP with wide limits of agreement in Bland-Altman plots of -21 to 34 mm Hg in the intensive-treatment group and -26 to 32 mm Hg in the standard-treatment group. Overall, there was poor agreement between clinic visit-to-visit variability and ambulatory BP variability with correlation coefficients for systolic and diastolic BP all <0.16. We observed a high correlation between first and second ambulatory BP ; however, the limits of agreement were wide in both the intensive group (-27 to 21 mm Hg) and the standard group (-23 to 20 mm Hg). Conclusions We found low concordance in BP and BP variability between clinic and ambulatory BP and second ambulatory BP . Results did not differ by treatment arm. These results reinforce the need for multiple BP measurements before clinical decision making.

Indexed as

AgedAged, 80 and overAntihypertensive AgentsBlood Pressure DeterminationBlood Pressure Monitoring, AmbulatoryHumansHypertensionMasked HypertensionMiddle AgedPatient Care PlanningWhite Coat HypertensionAntihypertensive Agentsambulatory blood pressure monitoringcircadian rhythmconcordancevariability

Identifiers

PMID31307270
PMCPMC6662121

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.