Evidence map›Paper›PMID 31307210›Full record

ArticleFASEB journal : official publication of the Federation of American Societies for Experimental Biology2019

Ileal interposition surgery targets the hepatic TGF-β pathway, influencing gluconeogenesis and mitochondrial bioenergetics in the UCD-T2DM rat model of diabetes.

Connie Hung, Eleonora Napoli, Catherine Ross-Inta, James Graham, Amanda L Flores-Torres, Kimber L Stanhope, Pascal Froment, Peter J Havel, Cecilia Giulivi

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 4 countries.

Connie HungDepartment of Molecular Biosciences, School of Veterinary Medicine, University of California, Davis, Davis, California, USA.
Eleonora NapoliDepartment of Molecular Biosciences, School of Veterinary Medicine, University of California, Davis, Davis, California, USA.
Catherine Ross-IntaDepartment of Molecular Biosciences, School of Veterinary Medicine, University of California, Davis, Davis, California, USA.
James GrahamDepartment of Nutrition, University of California, Davis, Davis, California, USA.
Amanda L Flores-TorresDepartment of Molecular Biosciences, School of Veterinary Medicine, University of California, Davis, Davis, California, USA.
Kimber L StanhopeDepartment of Molecular Biosciences, School of Veterinary Medicine, University of California, Davis, Davis, California, USA.
Pascal FromentUnité de Physiologie de la Reproduction et des Comportements, Institut National de la Recherche Agronomique, Unité Mixte de Recherche (UMR) 85, Paris, France.
Peter J HavelDepartment of Molecular Biosciences, School of Veterinary Medicine, University of California, Davis, Davis, California, USA.
Cecilia GiuliviDepartment of Molecular Biosciences, School of Veterinary Medicine, University of California, Davis, Davis, California, USA.
University of California, Davis · USInstitut National de la Recherche Agronomique · MAUniversity of California Davis Medical Center · US

Funding

Surgical amelioration of type 2 diabetes: Hormones, microbiota and mitochondriaRC1DK087307 · NIDDK · UNIVERSITY OF CALIFORNIA AT DAVIS · PI GIULIVI, CECILIA, HAVEL, PETER J · 2009 to 2010
$985k
6 · The paper itself

Abstract

Ileal interposition (IT) is a surgical procedure that increases the delivery of incompletely digested nutrients and biliary and pancreatic secretions to the distal intestinal mucosa. Here, we investigated the metabolic impact of this intervention in 2-mo-old prediabetic University of California, Davis type 2 diabetes mellitus rats by assessing liver gene expression at 1.5 mo post-IT surgery. Pathway analysis indicated decreased signaling

Indexed as

AnimalsBlood GlucoseDiabetes Mellitus, ExperimentalDiabetes Mellitus, Type 2Disease Models, AnimalEnergy MetabolismGlucagon-Like Peptide 1GluconeogenesisGlucoseIleumInsulinLipid MetabolismLiverMaleMitochondriaPhosphatidylinositol 3-KinasesBlood GlucoseGlucagon-Like Peptide 1GlucoseInsulinPhosphatidylinositol 3-KinasesSmad ProteinsTransforming Growth Factor betaIT surgerymetabolomicstype 2 diabetes mellitus

Identifiers

PMID31307210
PMCPMC6766639
OpenAlexW2957032458

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.