Evidence map›Paper›PMID 31306650›Full record

SynthesisAmerican journal of obstetrics and gynecology2020

Maternal disability and risk for pregnancy, delivery, and postpartum complications: a systematic review and meta-analysis.

Lesley A Tarasoff, Saranyah Ravindran, Hannan Malik, Dinara Salaeva, Hilary K Brown

Open access · greenAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in American journal of obstetrics and gynecology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 70 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
70citing papers in PubMed, 1 pooled it
14.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

70 citing papers in PubMed, 1 synthesis or guideline pooled it, 152 citations in OpenAlex.

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10 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Lesley A TarasoffInterdisciplinary Centre for Health and Society, University of Toronto Scarborough, Scarborough, Toronto, Canada; Azrieli Adult Neurodevelopmental Centre, Centre for Addiction and Mental Health, Toronto, Canada.
Saranyah RavindranDalla Lana School of Public Health, Toronto, Canada.
Hannan MalikInterdisciplinary Centre for Health and Society, University of Toronto Scarborough, Scarborough, Toronto, Canada.
Dinara SalaevaDalla Lana School of Public Health, Toronto, Canada.
Hilary K BrownInterdisciplinary Centre for Health and Society, University of Toronto Scarborough, Scarborough, Toronto, Canada; Dalla Lana School of Public Health, Toronto, Canada; Department of Psychiatry, Toronto, Canada; University of Toronto, and Women's College Research Institute, Women's College Hospital, Toronto, Canada. Electronic address: hk.brown@utoronto.ca.
Public Health Ontario · CAUniversity of Toronto · CACentre for Addiction and Mental Health · CA

Funding

Pregnancy in Women with Disabilities: Using Novel Methods to Characterize RiskR01HD092326 · NICHD · UNIVERSITY OF TORONTO · PI BROWN, HILARY, LUNSKY, YONA · 2017 to 2020
$590k
NICHD NIH HHS R01 HD092326
6 · The paper itself

Abstract

backgroundWomen with disabilities are increasingly becoming pregnant, and growing evidence suggests maternal disability may be associated with increased risk for perinatal complications.

objectiveA systematic review and meta-analysis were undertaken to examine the association between maternal disabilities and risk for perinatal complications. STUDY

designMedline, CINAHL, EMBASE, and PsycINFO were searched from inception to July 2018 for full-text publications in English on pregnancy, delivery, and postpartum complications in women with any disability and those with physical, sensory, and intellectual and developmental disabilities specifically. Searches were limited to quantitative studies with a comparison group of women without disabilities. Reviewers used standardized instruments to extract data from and assess the quality of included studies. Pooled odds ratios and 95% confidence intervals were generated using DerSimonian and Laird random effects models for outcomes with data available from ≥3 studies.

resultsThe review included 23 studies, representing 8,514,356 women in 19 cohorts. Women with sensory (pooled unadjusted odds ratio, 2.85, 95% confidence interval, 0.79-10.31) and intellectual and developmental disabilities (pooled unadjusted odds ratio, 1.10, 95% confidence interval, 0.76-1.58) had elevated but not statistically significant risk for gestational diabetes. Women with any disability (pooled unadjusted odds ratio, 1.45, 95% confidence interval, 1.16-1.82) and intellectual and developmental disabilities (pooled unadjusted odds ratio, 1.77, 95% confidence interval, 1.21-2.60) had increased risk for hypertensive disorders of pregnancy; risk was elevated but not statistically significant for women with sensory disabilities (pooled unadjusted odds ratio, 2.84, 95% confidence interval, 0.85-9.43). Women with any (pooled unadjusted odds ratio, 1.31, 95% confidence interval, 1.02-1.68), physical (pooled unadjusted odds ratio, 1.60, 95% confidence interval, 1.21-2.13), and intellectual and developmental disabilities (pooled unadjusted odds ratio, 1.29, 95% confidence interval, 1.02-1.63) had increased risk for cesarean delivery; risk among women with sensory disabilities was elevated but not statistically significant (pooled unadjusted odds ratio, 1.28, 95% confidence interval, 0.84-1.93). There was heterogeneity in all analyses, and 13 studies had weak-quality ratings, with lack of control for confounding being the most common limitation.

conclusionEvidence that maternal disability is associated with increased risk for perinatal complications demonstrates that more high-quality research is needed to examine the reasons for this risk and to determine what interventions could be implemented to support women with disabilities during the perinatal period.

Indexed as

Autism Spectrum DisorderCerebral PalsyComorbidityDevelopmental DisabilitiesDown SyndromeFemaleFetal Alcohol Spectrum DisordersHearing LossHumansIntellectual DisabilityNeurodevelopmental DisordersObstetric Labor ComplicationsPersons with DisabilitiesPregnancyPregnancy ComplicationsPuerperal Disorderscesarean deliverydevelopmental disabilitiesdisabled personsgestational diabetesmeta-analysispostpartum periodpregnancypregnancy complicationspregnancy-induced hypertensionsystematic review

Identifiers

PMID31306650
PMCPMC6937395
OpenAlexW2956249940

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.