Evidence map›Paper›PMID 31306647›Full record

ArticleNeuropharmacology2019

Amygdala group II mGluRs mediate the inhibitory effects of systemic group II mGluR activation on behavior and spinal neurons in a rat model of arthritis pain.

Mariacristina Mazzitelli, Volker Neugebauer

Open access · greenAbstract read
In one paragraph

Article in Neuropharmacology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 24 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Mariacristina MazzitelliDepartment of Pharmacology and Neuroscience, School of Medicine, Texas Tech University Health Sciences Center, Lubbock, TX, 79430-6592, USA.
Volker NeugebauerDepartment of Pharmacology and Neuroscience, School of Medicine, Texas Tech University Health Sciences Center, Lubbock, TX, 79430-6592, USA; Center of Excellence for Translational Neuroscience and Therapeutics, Texas Tech University Health Sciences Center, Lubbock, TX, 79430-6592, USA; Garrison Institute on Aging, Texas Tech University Health Sciences Center, Lubbock, TX, 79430-6592, USA. Electronic address: volker.neugebauer@ttuhsc.edu.
Texas Tech University · US

Funding

PAIN, NOCICEPTION, AND THE AMYGDALAR01NS038261 · NINDS · UNIVERSITY OF TEXAS MEDICAL BR GALVESTON · PI Volker Neugebauer, Igor Ponomarev · 1999 to 2026
$8.7M
Stress-induced descending facilitation from amygdala kappa opioid receptors in functional painR01NS106902 · NINDS · UNIVERSITY OF ARIZONA · PI NEUGEBAUER, VOLKER, PORRECA, FRANK · 2018 to 2022
$2.7M
Amygdala Serotonin Neurotransmission and Neuropathic PainR01NS081121 · NINDS · UNIVERSITY OF TEXAS MED BR GALVESTON · PI GREEN, THOMAS ARTHUR, NEUGEBAUER, VOLKER · 2013 to 2017
$2.3M
NINDS NIH HHS R01 NS038261NINDS NIH HHS R01 NS081121NINDS NIH HHS R01 NS106902
6 · The paper itself

Abstract

The amygdala plays a critical role in emotional-affective aspects of behaviors and pain modulation. The central nucleus of amygdala (CeA) serves major output functions, and neuroplasticity in the CeA is linked to pain-related behaviors in different models. Activation of G

Indexed as

Arthritis, ExperimentalAmino AcidsAmygdalaAnimalsArthralgiaBehavior, AnimalBridged Bicyclo Compounds, HeterocyclicCarrageenanCentral Amygdaloid NucleusExcitatory Amino Acid AgonistsExcitatory Amino Acid AntagonistsKaolinNociceptionPainPosterior Horn CellsRatsAmino AcidsBridged Bicyclo Compounds, HeterocyclicCarrageenanExcitatory Amino Acid AgonistsExcitatory Amino Acid AntagonistsKaolinLY 341495LY 379268metabotropic glutamate receptor 2metabotropic glutamate receptor 3Receptors, Metabotropic GlutamateXanthenesAmygdalaAnalgesiaBehaviorElectrophysiologyMetabotropic glutamate receptorNociceptionPainSpinal cord

Identifiers

PMID31306647
PMCPMC6745268
OpenAlexW2962118359

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.