Evidence map›Paper›PMID 31306507›Full record

ReviewPrenatal diagnosis2020

Placental MRI and its application to fetal intervention.

Rosalind Aughwane, Emma Ingram, Edward D Johnstone, Laurent J Salomon, Anna L David, Andrew Melbourne

Open access · hybridAbstract readReview
In one paragraph

Review in Prenatal diagnosis, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
12.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 67 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Toward Clinical Implementation of Magnetic Resonance Imaging for Placental Function.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2025
    Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. Developments in functional imaging of the placenta.The British journal of radiology · 2023
    Review
  15. Magnetic resonance imaging of the monkey fetal brain in utero.Investigative magnetic resonance imaging · 2022
    Article
  16. Placental MRI Predicts Fetal Oxygenation and Growth Rates in Sheep and Human Pregnancy.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2022
    Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 2 countries.

Rosalind AughwaneInstitute for Women's Health, University College London, London, UK.
Emma IngramDivision of Developmental Biology & Medicine, University of Manchester, Manchester, UK.
Edward D JohnstoneDivision of Developmental Biology & Medicine, University of Manchester, Manchester, UK.
Laurent J SalomonHôpital Necker-Enfants Malades, AP-HP, EHU PACT and LUMIERE Platform, Université Paris Descartes, Paris, France.ORCID 0000-0003-0627-4347
Anna L DavidInstitute for Women's Health, University College London, London, UK.
Andrew MelbourneSchool of Biomedical Engineering and Imaging Sciences, King's College London, London, UK.ORCID 0000-0001-7667-3947
University of Manchester · GBHôpital Necker-Enfants Malades · FRKing's College London · GBLondon Women's Clinic · GBNational Institute for Health Research · GB

Funding

Wellcome TrustWellcome Trust 210182/Z/18/ZWellcome Trust NS/A000027/1
6 · The paper itself

Abstract

objectiveMagnetic resonance imaging (MRI) of placental invasion has been part of clinical practice for many years. The possibility of being better able to assess placental vascularization and function using MRI has multiple potential applications. This review summarises up-to-date research on placental function using different MRI modalities.

methodWe discuss how combinations of these MRI techniques have much to contribute to fetal conditions amenable for therapy such as singletons at high risk for fetal growth restriction (FGR) and monochorionic twin pregnancies for planning surgery and counselling for selective growth restriction and transfusion conditions.

resultsThe whole placenta can easily be visualized on MRI, with a clear boundary against the amniotic fluid, and a less clear placental-uterine boundary. Contrasts such as diffusion weighted imaging, relaxometry, blood oxygenation level dependent MRI and flow and metabolite measurement by dynamic contrast enhanced MRI, arterial spin labeling, or spectroscopic techniques are contributing to our wider understanding of placental function.

conclusionThe future of placental MRI is exciting, with the increasing availability of multiple contrasts and new models that will boost the capability of MRI to measure oxygen saturation and placental exchange, enabling examination of placental function in complicated pregnancies.

Indexed as

Diffusion Magnetic Resonance ImagingFemaleFetal Growth RetardationFetal TherapiesFetofetal TransfusionHumansMagnetic Resonance ImagingMagnetic Resonance SpectroscopyPlacentaPlacental InsufficiencyPregnancyPrenatal Diagnosis

Identifiers

PMID31306507
PMCPMC7027916
OpenAlexW2958183105

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.