Evidence map›Paper›PMID 31306402›Full record

SynthesisThe Pediatric infectious disease journal2019

Respiratory Virus Epidemiology Among US Infants With Severe Bronchiolitis: Analysis of 2 Multicenter, Multiyear Cohort Studies.

Kohei Hasegawa, Tadahiro Goto, Atsushi Hirayama, Federico R Laham, Jonathan M Mansbach, Pedro A Piedra, Carlos A Camargo

Abstract readMeta-Analysis
In one paragraph

Synthesis in The Pediatric infectious disease journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
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  5. Observational
  6. Article
  7. Article
  8. Review
  9. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kohei HasegawaFrom the Department of Emergency Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.
Tadahiro GotoFrom the Department of Emergency Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.
Atsushi HirayamaNational Cerebral and Cardiovascular Center, Suita, Osaka, Japan.
Federico R LahamDepartment of Infectious Disease, Arnold Palmer Hospital for Children, Orlando, Florida.
Jonathan M MansbachDepartment of Medicine, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts.
Pedro A PiedraDepartments of Molecular Virology and Microbiology and Pediatrics, Baylor College of Medicine, Houston, Texas.
Carlos A CamargoFrom the Department of Emergency Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.

Funding

Host genetics, early-life microbiome, and childhood asthma: MARC-43 BostonUH3OD023253 · OD · MASSACHUSETTS GENERAL HOSPITAL · PI CARLOS ARTURO CAMARGO · 2018 to 2026
$12.1M
Nasal microRNA during bronchiolitis and age 6y asthma phenotypes: MARC-35 cohortR01AI127507 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI CAMARGO, CARLOS ARTURO, FREISHTAT, ROBERT J · 2017 to 2021
$8.0M
Host genetics, early-life microbiome, and childhood asthma: MARC-43 BostonUG3OD023253 · OD · MASSACHUSETTS GENERAL HOSPITAL · PI CAMARGO, CARLOS ARTURO · 2016 to 2024
$6.8M
Prospective Cohort Study of Severe Bronchiolitis and Risk of Recurrent WheezingU01AI087881 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI CAMARGO, CARLOS ARTURO · 2011 to 2016
$6.2M
Airway dual-transcriptomics in bronchiolitis and risk of asthma: MARC-35 cohortR01AI137091 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI HASEGAWA, KOHEI · 2018 to 2022
$4.3M
Infant specific-IgE, rhinovirus-C bronchiolitis, and incident asthma in MARC-35R01AI114552 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI CAMARGO, CARLOS ARTURO · 2015 to 2019
$4.2M
Airway metagenome & metabolome in bronchiolitis and risk of asthma: MARC-35 cohortR01AI134940 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI HASEGAWA, KOHEI · 2018 to 2022
$4.0M
Prospective Multicenter Study of Bronchiolitis Admissions: Etiology & DispositionU01AI067693 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI CAMARGO, CARLOS ARTURO · 2007 to 2010
$3.6M
Cytokines & transcriptomes in rhinovirus bronchiolitis and risk of incident asthmaR21HL129909 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI HASEGAWA, KOHEI · 2015 to 2016
$506k
NHLBI NIH HHS R21 HL129909NIAID NIH HHS R01 AI114552NIAID NIH HHS R01 AI127507NIAID NIH HHS R01 AI134940NIAID NIH HHS R01 AI137091NIAID NIH HHS U01 AI067693NIAID NIH HHS U01 AI087881NIH HHS UG3 OD023253NIH HHS UH3 OD023253
6 · The paper itself

Abstract

In 2 multicenter cohort studies of 2912 infants hospitalized for bronchiolitis during 2007-2014, the 5 most common pathogens were RSV (76.5%), rhinovirus (23.8%), coronavirus (6.9%), adenovirus (6.4%) and human metapneumovirus (6.0%). Hospitalization months significantly differed for these common pathogens (P ≤ 0.01), except for coronavirus (P = 0.30). There was a significant heterogeneity in temporal patterns by region in RSV-A and -B (both P < 0.001).

Indexed as

Age FactorsBronchiolitisCohort StudiesFemaleHumansInfantInfant, NewbornMaleMulticenter Studies as TopicPublic Health SurveillanceSeasonsUnited States

Identifiers

PMID31306402
PMCPMC6636850

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.