Evidence map›Paper›PMID 31306253›Full record

ReviewCurrent opinion in psychiatry2019

The promise of neurobiological research in anorexia nervosa.

Joanna E Steinglass, Maya Dalack, Karin Foerde

Abstract readReview
In one paragraph

Review in Current opinion in psychiatry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Anorexia Nervosa Across the Lifespan: A Review of Recent Literature.Focus (American Psychiatric Publishing) · 2024
    Review
  4. Eating Disorders: Updates and Innovations.Focus (American Psychiatric Publishing) · 2024
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Joanna E SteinglassDepartment of Psychiatry, Columbia University Irving Medical Center, New York State Psychiatric Institute, New York, New York, USA.
Maya Dalack
Karin Foerde

Funding

Neural Mechanisms of Food Choice in Anorexia NervosaR01MH105452 · NIMH · NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC · PI SHOHAMY, DAPHNA, STEINGLASS, JOANNA E · 2015 to 2018
$2.3M
Training and Mentoring in Neurocognitive Mechanisms of Eating DisordersK24MH113737 · NIMH · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI STEINGLASS, JOANNA E · 2018 to 2022
$614k
NIMH NIH HHS K24 MH113737NIMH NIH HHS R01 MH105452
6 · The paper itself

Abstract

purpose of reviewThis article reviews new research in the context of existing literature to identify approaches that will advance understanding of the persistence of anorexia nervosa. RECENT

findingsNeuroscience research in anorexia nervosa has yielded disparate findings: no definitive neural mechanism underlying illness vulnerability or persistence has been identified and no clear neural target for intervention has emerged. Recent advances using structural and functional neuroimaging research, as well as new techniques for applying and combining these approaches, have led to a refined understanding of changes in neural architecture among individuals who are acutely ill, have undergone renourishment, or are in recovery/remission. In particular, advances have come from the incorporation of computational and translational approaches, as well as efforts to link experimental paradigms with illness-relevant behavior. Recent findings converge to suggest abnormalities in systems involved in reward learning and processing among individuals with anorexia nervosa. SUMMARY: Anorexia nervosa is associated with neurobiological abnormalities. Aberrant learning and reward processing may contribute to the persistence of illness. To better utilize new techniques to understand the neural mechanisms of persistent anorexia nervosa, it may help to distinguish stages of illness and to link neurobiology with maladaptive behavior.

Indexed as

NeurobiologyAnorexia NervosaBiomedical ResearchBrainFeeding BehaviorFunctional NeuroimagingHumansReward

Identifiers

PMID31306253
PMCPMC6768709

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.