ArticleAmerican journal of clinical pathology2019
Migration of Talc From the Perineum to Multiple Pelvic Organ Sites.
Article in American journal of clinical pathology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed, 13 citations in OpenAlex.
- Review
- Decoding the Link Between Talcum Powder and Ovarian Cancer: A Comprehensive Review.Journal of clinical medicine · 2025Review
- Asbestos Exposure and Ovarian Cancer: A Meta-analysis.Safety and health at work · 2024Review
- Association of genital talc and douche use in early adolescence or adulthood with uterine fibroids diagnoses.American journal of obstetrics and gynecology · 2023Article
- Talc, body powder, and ovarian cancer: A summary of the epidemiologic evidence.Gynecologic oncology · 2021Review
- Primary Ovarian Mesothelioma: A Case Series with Electron Microscopy Examination and Review of the Literature.Cancers · 2021Article
- Analysis of particles from hamster lungs following pulmonary talc exposures: implications for pathogenicity.Particle and fibre toxicology · 2020Article
- The effect of talc particles on phagocytes in co-culture with ovarian cancer cells.Environmental research · 2020Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
Abstract
objectivesGenital talc use is associated with increased risk for ovarian carcinoma in epidemiologic studies. Finding talc in pelvic tissues in women with ovarian carcinoma who have used talc is important in documenting exposure and assessing talc's biologic potential, but tissue-based morphology studies have been rarely reported.
methodsWe report five patient cases with documented perineal talc use, each of whom had talc (by both polarized light and scanning electron microscopy) in multiple pelvic sites distant from the perineum. Six negative-exposure control patients were also analyzed.
resultsTalc particles were found in exposed patients, typically within two or more of the following locations: pelvic region lymph nodes, cervix, uterine corpus, fallopian tubes, and ovaries.
conclusionsOur report adds new insights into the biologic potential of talc and suggests additional anatomic sites that should be closely examined for talc by oncologic surgical pathologists in the setting of perineal talc use.
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Registered trials
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