ArticleMedicine2019
The risk of end-stage renal disease in systemic lupus erythematosus: A nationwide population-based study in Korea.
Article in Medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 30 citations in OpenAlex.
- Risk of chronic kidney disease in newly diagnosed SLE with preserved renal function: a national study.Rheumatology (Oxford, England) · 2026Article
- Serum and urinary soluble CD163 in children with active lupus nephritis.Pediatric rheumatology online journal · 2026Article
- Hydroxychloroquine Associated With Lower Glomerular Filtration Rate Decline in Lupus Nephritis.Arthritis care & research · 2026Article
- Rituximab Treatment in Lupus Nephritis Resistant to Conventional Therapy: A Single-Centre Experience.Mediterranean journal of rheumatology · 2025Article
- Development and validation of a predictive model for end-stage renal disease in systemic lupus erythematosus patients.Rheumatology international · 2024Article
- Review
- Prevalence and outcomes of end-stage kidney disease in patients with systemic lupus erythematous: a population-based study.Rheumatology international · 2024Article
- Incident dementia in kidney transplantation recipients: a matched comparative nationwide cohort study in South Korea.Kidney research and clinical practice · 2023Article
- Prevalence, incidence, and treatment of anaemia in patients with non-dialysis-dependent chronic kidney disease: findings from a retrospective real-world study in Italy.Journal of nephrology · 2023Observational
- Non-traditional risk factors of progression of chronic kidney disease in adult population: a scoping review.Frontiers in medicine · 2023Article
- The Etiology of Kidney Failure in Indonesia: A Multicenter Study in Tertiary-Care Centers in Jakarta.Annals of global health · 2023Article
- Dose adjustment of rheumatology and allergy/immunology medications in chronic kidney disease: awareness and knowledge among internal medicine housestaff.Proceedings (Baylor University. Medical Center) · 2023Article
- Multidisciplinary Lupus Nephritis Clinic Reduces Time to Renal Biopsy and Improves Care Quality.ACR open rheumatology · 2022Article
- High risk of depression, anxiety, and an unfavorable complex comorbidity profile is associated with SLE: a nationwide patient-level study.Arthritis research & therapy · 2022Article
- Chronic Kidney Disease and SGLT2 Inhibitors: A Review of the Evolving Treatment Landscape.Advances in therapy · 2022Review
- Incident Parkinson's disease in kidney transplantation recipients: a nationwide population-based cohort study in Korea.Scientific reports · 2021Article
- The Influence of Renal Dialysis on All-Cause Mortality in Older Patients with Hip Fracture: a Korean Nationwide Cohort Study.Journal of Korean medical science · 2020Article
- An Update on the Diagnosis and Management of Lupus Nephritis.Current rheumatology reports · 2020Review
- Smoking and risk of incident end-stage kidney disease in general population: A Nationwide Population-based Cohort Study from Korea.Scientific reports · 2019Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Systemic lupus erythematosus (SLE) is known to be one of the leading causes of end-stage renal disease (ESRD). The aim of this study was to estimate the incidence rate of ESRD and the risk for progression to ESRD in SLE patients compared to the general population.A total of 21,253 SLE patients were extracted from the Korean National Health Insurance Service database between 2008 and 2013. Age-and sex-matched controls (n = 106,265) were randomly sampled in a 5:1 ratio from non-SLE individuals. Both cohorts were followed up for development of ESRD until 2015.During the median 7.53 years of follow-up, 533 (2.51%) cases of ESRD were newly developed in SLE patients and 145 (0.14%) cases in matched controls (incidence rate: 4.075 and 0.219 per 1000 person-year, respectively). SLE patients were at higher risk for ESRD development compared to matched controls (hazard ratio [HR], 9.84; 95% confidence interval [CI] 8.10-11.96) after multivariate adjustment. In subgroup analysis, the risk for ESRD was higher in male (HR, 7.76; 95% CI 5.07-11.90) and female patients with SLE (HR, 10.48; 95% CI 8.41-13.07) than in matched controls. When analyzed by age group, the younger the age, the higher the risk of ESRD versus non-SLE matched controls; this result was also significant after adjustment. In subgroup analysis according to comorbidities, the SLE group had a significantly higher risk of ESRD than the non-SLE group in almost all subgroups.SLE was associated with an increased incidence of ESRD.
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