Evidence map›Paper›PMID 31305418›Full record

ArticleMedicine2019

Acute pulmonary thromboembolism caused by factor V Leiden mutation in South Korea: A case report.

Hun Jee Choe, Koung Jin Suh, Ji Yun Lee, Minyoung Kim, Man Jin Kim, Sung Sup Park, Ji-Won Kim, Se Hyun Kim, Jin Won Kim, Jeong-Ok Lee and 5 more

Open access · goldAbstract readCase Reports
In one paragraph

Article in Medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 2 institutions in 1 country.

Hun Jee ChoeDepartment of Internal Medicine, Seoul National University, Seoul National University Bundang Hospital, Seongnam.
Koung Jin SuhDepartment of Internal Medicine, Seoul National University, Seoul National University Bundang Hospital, Seongnam.
Ji Yun LeeDepartment of Internal Medicine, Seoul National University, Seoul National University Bundang Hospital, Seongnam.
Minyoung KimDepartment of Laboratory Medicine, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Republic of Korea.
Man Jin KimDepartment of Laboratory Medicine, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Republic of Korea.
Sung Sup ParkDepartment of Laboratory Medicine, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Republic of Korea.
Ji-Won KimDepartment of Internal Medicine, Seoul National University, Seoul National University Bundang Hospital, Seongnam.
Se Hyun KimDepartment of Internal Medicine, Seoul National University, Seoul National University Bundang Hospital, Seongnam.
Jin Won KimDepartment of Internal Medicine, Seoul National University, Seoul National University Bundang Hospital, Seongnam.
Jeong-Ok LeeDepartment of Internal Medicine, Seoul National University, Seoul National University Bundang Hospital, Seongnam.
Yu Jung KimDepartment of Internal Medicine, Seoul National University, Seoul National University Bundang Hospital, Seongnam.
Keun-Wook LeeDepartment of Internal Medicine, Seoul National University, Seoul National University Bundang Hospital, Seongnam.
Jee Hyun KimDepartment of Internal Medicine, Seoul National University, Seoul National University Bundang Hospital, Seongnam.
Soo-Mee BangDepartment of Internal Medicine, Seoul National University, Seoul National University Bundang Hospital, Seongnam.
Jong Seok LeeDepartment of Internal Medicine, Seoul National University, Seoul National University Bundang Hospital, Seongnam.
Seoul National University Bundang Hospital · KRSeoul National University Hospital · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

rationaleAlthough Factor V Leiden (FVL) mutation is a major cause of inherited thrombophilia in Western populations; the mutation is extremely rare in Asia. PATIENT CONCERNS: Here we report a case of a 28-year old Korean woman admitted to our hospital with extensive pulmonary embolism. DIAGNOSIS: She was heterozygous for FVL mutation up on evaluation, and screening for asymptomatic family members also revealed heterozygous FVL mutation for her mother.

interventionsEnoxaparin 1 mg/kg was initiated, followed by rivaroxaban 15 mg every 12 hours. OUTCOMES: The patient showed improvement in both subjective dyspnea and right ventricular dysfunction and was successfully discharged after five hospital days. LESSONS: FVL mutation screening may be considered in Asian patients with thrombophilia of uncertain etiology in the future.

Indexed as

MutationAdultAsian PeopleDiagnosis, DifferentialFactor VFemaleHumansPulmonary EmbolismRepublic of KoreaThrombophiliaFactor Vfactor V Leiden

Identifiers

PMID31305418
PMCPMC6641677
OpenAlexW2956427631

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.