Evidence map›Paper›PMID 31305084›Full record

ArticleOrganic letters2019

Factors Controlling Reactivity in the Hydrogen Atom Transfer and Radical Addition Steps of a Radical Relay Cascade.

Yike Zou, Xiao-Song Xue, Yifan Deng, Amos B Smith, K N Houk

Open access · greenAbstract read
In one paragraph

Article in Organic letters, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.8field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 10 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Yike ZouDepartment of Chemistry and Biochemistry , University of California , Los Angeles , California 90095-1569 , United States.
Xiao-Song XueDepartment of Chemistry and Biochemistry , University of California , Los Angeles , California 90095-1569 , United States.ORCID 0000-0003-4541-8702
Yifan DengDepartment of Chemistry , University of Pennsylvania , 231 South 34th Street , Philadelphia , Pennsylvania 19104 , United States.
Amos B SmithDepartment of Chemistry , University of Pennsylvania , 231 South 34th Street , Philadelphia , Pennsylvania 19104 , United States.ORCID 0000-0002-1712-8567
K N HoukDepartment of Chemistry and Biochemistry , University of California , Los Angeles , California 90095-1569 , United States.ORCID 0000-0002-8387-5261
University of California, Los Angeles · USUniversity of Pennsylvania · US

Funding

Bioorthogonal CycloadditionsR01GM109078 · NIGMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI HOUK, KENDALL N · 2015 to 2018
$1.1M
NIGMS NIH HHS R01 GM109078
6 · The paper itself

Abstract

DFT exploration of 1,5- and 1,6-hydrogen atom transfers (HAT), radical addition, and relay to alkene is reported. The reactivity of 1,5- and 1,6-HAT are similar. We also explored reactions involving a multiple radical transferring process. Initially generated radicals undergo a multiple HAT process to form multiple bonds in a "relay" fashion, provided by exquisitely balanced rates.

Indexed as

HydrogenHydrogen BondingKineticsHydrogen

Identifiers

PMID31305084
PMCPMC6760911
OpenAlexW2959820705

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.