ArticleForensic sciences research2019
Wastewater analysis for nicotine, cocaine, amphetamines, opioids and cannabis in New York City.
Article in Forensic sciences research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 55 citations in OpenAlex.
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- Laboratory Assessment of Wastewater as Surveillance Tool for West Nile Virus, United States.Emerging infectious diseases · 2026Article
- A mixed-methods evaluation of a statewide naloxone distribution project: considerations for future implementation of opioid overdose prevention initiatives.BMC public health · 2026Article
- Global wastewater microbiome reveals core bacterial community and viral diversity with regional antibiotic resistance patterns.mSystems · 2025Article
- Construction and Comparison of UPLC-QE-Orbitrap-MS and UPLC-MS/MS Methods for the Detection of Diazepam Residues in Complex Aquatic Matrices.Foods (Basel, Switzerland) · 2025Article
- The effects of methamphetamine intoxication on acute kidney injury in Iraqi male addicts.Toxicology reports · 2025Article
- Comparative analysis of qPCR and metagenomics for detecting antimicrobial resistance in wastewater: a case study.BMC research notes · 2025Article
- The impact of methamphetamine on liver injury in Iraqi male addicts.Toxicology reports · 2024Article
- Understanding common population markers for SARS-CoV-2 RNA normalization in wastewater - A review.Chemosphere · 2023Review
- Trends and challenges in analytical chemistry for multi-analysis of illicit drugs employing wastewater-based epidemiology.Analytical and bioanalytical chemistry · 2023Article
- Long-term wastewater-based surveillance and impacts of the COVID-19 pandemic on drug use trends in a U.S. Northeast rural town.The Science of the total environment · 2023Article
- Leveraging an established neighbourhood-level, open access wastewater monitoring network to address public health priorities: a population-based study.The Lancet. Microbe · 2023Article
- Methamphetamine Disturbs Gut Homeostasis and Reshapes Serum Metabolome, Inducing Neurotoxicity and Abnormal Behaviors in Mice.Frontiers in microbiology · 2022Article
- Lessons learned from SARS-CoV-2 measurements in wastewater.The Science of the total environment · 2021Article
- "Waste Not, Want Not" - Leveraging Sewer Systems and Wastewater-Based Epidemiology for Drug Use Trends and Pharmaceutical Monitoring.Journal of medical toxicology : official journal of the American College of Medical Toxicology · 2021Article
- Luteolin Alleviates Methamphetamine-Induced Hepatotoxicity by Suppressing the p53 Pathway-Mediated Apoptosis, Autophagy, and Inflammation in Rats.Frontiers in pharmacology · 2021Article
- High-throughput multi-residue quantification of contaminants of emerging concern in wastewaters enabled using direct injection liquid chromatography-tandem mass spectrometry.Journal of hazardous materials · 2020Article
- Methamphetamine Inhibits Long-Term Memory Acquisition and Synaptic Plasticity by Evoking Endoplasmic Reticulum Stress.Frontiers in neuroscience · 2020Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
According to current surveys and overdoses data, there is a drug crisis in the USA. Wastewater-based epidemiology (WBE) is an evolving discipline that analyses wastewater samples to detect drugs and metabolites to estimate drug consumption in a certain community. This study demonstrates how drug relative presence could be tracked by testing wastewater, providing real-time results, in different boroughs in New York City throughout 1 year. We developed and fully validated two analytical methods, one for 21 drugs and metabolites, including nicotine, cocaine, amphetamines, opioids and cannabis markers; and another for the normalization factor creatinine. Both methods were performed by liquid chromatography tandem mass spectrometry (LC-MS/MS) using positive electrospray ionization, achieving a limit of quantification of 5-10 ng/L for drugs and metabolites, and 0.01 mg/L for creatinine. These methods were applied to 48 one-time grab wastewater samples collected from six wastewater treatment plants in New York City (Manhattan, The Bronx, Queens and Brooklyn), eight different times throughout 2016, before and after major holidays, including Memorial Day, 4th of July, Labour Day and New Year's. In this study, the drug group normalized concentrations present in the wastewater samples, in decreasing order, were cocaine, nicotine, opioids, cannabis and amphetamines. When looking at individual compounds, the one with the highest normalized concentration was benzoylecgonine (BE), followed by cotinine, morphine and 11-
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