ArticleInternational journal of cardiology. Heart & vasculature2019
Aortic stiffness is independently associated with interstitial myocardial fibrosis by native T1 and accelerated in the presence of chronic kidney disease.
Article in International journal of cardiology. Heart & vasculature, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03749551 (TowaRds Understanding the phEnoTYPEs of Cardiovascular Dysfunction in Patients With Chronic Kidney Disease and HaemoDialysis Using Cardiovascular Magnetic Resonance Imaging - TRUE-Type-CKD Study), which is not on this map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
TowaRds Understanding the phEnoTYPEs of Cardiovascular Dysfunction in Patients With Chronic Kidney Disease and HaemoDialysis Using Cardiovascular Magnetic Resonance Imaging - TRUE-Type-CKD Study
Who cites it
11 citing papers in PubMed, 27 citations in OpenAlex.
- Prevalence and risk factors of pulmonary hypertension in maintenance hemodialysis patients based on echocardiography.Medicine · 2026Article
- Evaluation of cardiac remodeling in pediatric chronic kidney disease by cardiovascular magnetic resonance.BMC cardiovascular disorders · 2024Article
- Beyond Quadruple Therapy and Current Therapeutic Strategies in Heart Failure with Reduced Ejection Fraction: Medical Therapies with Potential to Become Part of the Therapeutic Armamentarium.International journal of molecular sciences · 2024Review
- Cardiac Imaging Biomarkers in Chronic Kidney Disease.Biomolecules · 2023Review
- Cardiac magnetic resonance imaging parameters show association between myocardial abnormalities and severity of chronic kidney disease.Frontiers in cardiovascular medicine · 2022Article
- TCardiac failure review · 2022Review
- Pathophysiology and consequences of arterial stiffness in children with chronic kidney disease.Pediatric nephrology (Berlin, Germany) · 2021Review
- Cardiac biomarkers in chronic kidney disease are independently associated with myocardial edema and diffuse fibrosis by cardiovascular magnetic resonance.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2021Article
- Impact of aortic stiffness by velocity-encoded magnetic resonance imaging on late gadolinium enhancement to predict cardiovascular events.International journal of cardiology. Heart & vasculature · 2020Article
- Cardiac Remodeling in Chronic Kidney Disease.Toxins · 2020Review
- Chronic kidney disease with elevated myocardial native T1 - Is this only due to myocardial fibrosis?International journal of cardiology. Heart & vasculature · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors at 3 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPatients with chronic kidney disease (CKD) have considerable cardiovascular morbidity and mortality. Aortic stiffness is an independent predictor of cardiovascular risk and related to left ventricular remodeling and heart failure. Myocardial fibrosis is the pathophysiological hallmark of the failing heart. METHODS AND
resultsAn observational study of consecutive CKD patients (
conclusionsAortic stiffness and interstitial myocardial fibrosis are interrelated; this association is accelerated in the presence of CKD, but independent of LGE. Our findings reiterate the significant contribution of CKD-related factors to the pathophysiology of cardiovascular remodeling.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.